Polycrystalline bis(dialkyldithiophosphato)Pt(II) complexes of the form [Pt{S2P(OR)2}2] (R = ethyl, iso-propyl, iso-butyl, sec-butyl or cyclo-hexyl group) were studied using solid-state 31P and 195Pt NMR spectroscopy, to determine the influence of R to the structure of the central chromophore. The measured anisotropic chemical shift (CS) parameters for 31P and 195Pt afford more detailed chemica...

The incorporation of a gem-dimethyl group at the 5-position of a chiral oxazolidinone biases the conformation of the adjacent C(4)-stereodirecting group such that the gem-dimethyl-4-iso-propyl combination mimics a C(4)-tert-butyl group, providing higher levels of stereocontrol than a simple 4-iso-propyloxazolidinone. The generality of this principle is demonstrated with applications in stereose...

New derivatives of synthetic 5,5-diphenylhydantoin (phenytoin) were prepared by N-alkylation with 1,3-dibromopropane. Subsequent treatment with sodium azide led to the respective azide. Reaction of the azide with phenylacetylene and 2-hydroxy-3-butyne and oxidation of the resulting alcohol with MnO2 resulted in three triazolic compounds that were evaluated in vitro for their antiviral activity ...

Nine compounds, 3-hydroxy-4,5-dimethoxyphenyl-beta-D-glucopyranoside (1), beta-D-fructfuranosyl-alpha-D-(6-vanilloyl)-glucopyranoside (2), beta-D-fructfuranosyl-alpha-D-(6-syringyl)-glucopyranoside (3), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2-methoxyphenoxy]propyl-beta-D-glucopyranoside (4), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl...

The carcinogen 1-[14C]propyl-1-nitrosourea (PNU) was readily absorbed from the rat gut, and the radioactivity was excreted mainly in the urine and expired air. The urinary metabolites of PNU were 1-propylurea and urea. 1-Propylurea was shown to be excreted largely unchanged in the urine. Both [14C]PNU and 1-[14C]propylurea were found to be eliminated rapidly from the rat body. Besides cO2 from ...

The search for alternative fuels that can limit the use of traditional fossil to power internal combustion engines is one main tasks faced by both modern automotive industry and energy industry. This paper presents experimental tests a compression ignition engine, in which conventional fuel, i.e., diesel, was partially replaced with propyl alcohol, renewable biofuel. Studies on co-combustion di...

The induction of 5-aminolaevulinate synthase and of cytochrome P-450 by short-chain aliphatic alcohols was compared in primary cultures ofchicken-embryo hepatocytes. Isopropyl alcohol, isobutanol, pentan-1 -ol and isopentanol alone caused up to a 4-fold increase in 5-aminolaevulinate synthase, whereas ethanol and propan-1-ol did not. Induction of the synthase by isopentanol was maximal at 8 h, ...

Commercially available Purolite CT151 demonstrated to be an efficient acid catalyst for the synthesis of alkyl levulinates via alcoholysis furfuryl alcohol (FA) at mild temperatures (80–120 °C) and short reaction time (5 h). Reaction conditions were first optimized ethyl levulinate then tested preparation methyl-, propyl-, isopropyl-, butyl, sec-butyl- allyl levulinate. Preliminary scale-up tes...