Objectives 1) Analyze the potential of amyloid beta (A)-oligomer concentrations in cerebrospinal fluid (CSF) to diagnose and predict progression to Alzheimer's disease (AD) in a large clinical study sample. 2) Monitor A-oligomer concentrations overtime , both in early and advanced stages of AD. 3) Examine the relation between A-oligomer levels in CSF and cognitive functioning. Methods 24 Non-de...

Half sandwich complexes of titanium bearing eta1 or eta2 bound nitroxide ligands are highly active catalysts for the polymerisation of propylene to high molecular weight atactic poly(propylene).

It has been found that propylene glycol vapor dispersed into the air of an enclosed space produces a marked and rapid bactericidal effect on microorganisms introduced into such an atmosphere in droplet form. Concentrations of 1 gm. of propylene glycol vapor in two to four million cc. of air produced immediate and complete sterilization of air into which pneumococci, streptococci, staphylococci,...

The surfaces of chemically synthesized Au nanoparticles have been modified with d- or l-cysteine to render them chiral and enantioselective for adsorption of chiral molecules. Their enantioselective interaction with chiral compounds has been probed by optical rotation measurements during exposure to enantiomerically pure and racemic propylene oxide. The ability of optical rotation to detect ena...

A study of the activity of deoxyribonucleotide-substituted analogs of the hammerhead domain of RNA catalysis has led to the design of a 14mer oligomer composed entirely of deoxyribonucleotides that promotes the cleavage of an RNA substrate. Characterization of this reaction with sequence variants and mixed DNA/RNA oligomers shows that, although the all-deoxyribonucleotide oligomer is less effic...

• The molecular chaperone CCT has functions in addition to protein folding. oncogenic transcription factor STAT3 binds oligomer. is not an obligate folding substrate of CCT. Reduction levels leads enhanced phosphorylation MCF7 cells. Sequestration by may provide a means regulate phosphorylation. Chaperonin Containing Tailless complex polypeptide 1 (CCT) essential required for the abundant prote...

A rapid headspace-gas chromatography (HS-GC) method was developed for the analysis of ethylene glycol and propylene glycol in plasma and serum specimens using 1,3-propanediol as the internal standard. The method employed a single-step derivitization using phenylboronic acid, was linear to 200 mg/dL and had a lower limit of quantitation of 1 mg/dL suitable for clinical analyses. The analytical m...

The propylene production with 1-butanol co-feeding for methanol in relation to propylene process (MTP) at 440-490 ̊C temperature range and at 0.9-15 hr-1 WHSV range over H-ZSM-5 zeolite catalyst is assessed in a isothermal fixed-bed reactor. The feedings here are of: pure 1-butanol, pure methanol and a 1-butanol and methanol mixture. The effect of 1-butanol co-feeding on selectivity of propylene...