We hypothesised that different endocrine profiles associated with pre-ovulatory follicle (POF) size would impact on uterine prostanoid pathways and thereby modulate the histotroph composition. Beef cows (n=15 per group) were hormonally manipulated to have small (SF-SCL group) or large (LF-LCL group) pre-ovulatory follicles (POF) and corpora lutea (CL). Seven days after induction of ovulation, a...

Glaucoma is a devastating disease that causes damage to the optic nerve and loss of visual function; it is the main cause of blindness in adults. Previous studies have shown that increased intraocular pressure (IOP) is the major risk factor for glaucoma and its progression. 3) With regard to therapy for glaucoma, topical medications are usually chosen as the primary treatment since reducing IOP...

The present study aimed to evaluate the GSH and MDA levels in dog’s serum vital organs of aborted fetuses, after application two abortifacient. Animals group I (n = 6) were treated twice with subcutaneous injection 10 mg/kg aglepristone II 3) received prostaglandin F2α at a dose 125 μg/kg every 12 hours until abortion process completed. Hematologic examinations sedimentation rates performed bit...

The prostanoid pathway converts polyunsaturated fatty acids (PUFAs) into bioactive lipid mediators, including prostaglandins, thromboxanes and prostacyclins, all of which play vital roles in the immune and reproductive systems in most animal phyla. In crustaceans, PUFAs and prostaglandins have been detected and often associated with female reproductive maturation. However, the presence of prost...