A 31-year-old Japanese man had visited India three times on business between August 2008 and April 2009. The initial lesion appeared in December 2009 as a single subcutaneous painless nodule on the neck, and the lesions gradually increased in number. In April 2010 he expelled worm fragments. He was referred to us in May 2010. Characteristic skin biopsy findings (protoscolex and invaginated neck...

The need to identify improved therapy against cystic echinococcosis (CE) has motivated pharmacology-based research. The comparative pharmacological performances of the benzimidazole compounds flubendazole (FLBZ) and albendazole (ABZ) were addressed here. The goals of the work were as follows: (i) to evaluate the ex vivo activities of FLBZ, ABZ, and their respective metabolites against Echinococ...

Echinococcosis caused by the larval form of Echinococcus granulosus (E. granulosus) is known as an important zoonotic disease in various parts of the world, including Iran. The genetic diversity of this parasite is very high, particularly in areas where the disease is endemic. It has been suggested in the literature from different parts of the world that diverse facto...

The aim of this study was to obtain uniformity in strobilar development of Echinococcus multilocularis from protoscoleces in vitro. The isolate of E. multilocularis used was derived initially from a human case in France and subsequently maintained in the laboratory by intraperitoneal passage in Meriones unguiculatus. Protoscoleces used for culture were obtained using preparative procedures in w...

Hydatid cyst or Cystic Echinococcosis continues to be an important problem in terms of public health as well animal regions with low socio-cultural level where preventive medicine cannot fully performed. In this study, it is aimed make evaluation about the situation cattle slaughtered region by examining lungs and livers a private abottoir Eskişehir hydatid cyst. For purpose, 150 slaughtering w...

Abstract Alveolar echinococcosis (AE) is caused by the larval stage of Echinococcus multilocularis . Chemotherapy for AE involves albendazole (ABZ), which has shown insufficient efficacy. More effective chemotherapy needed. Previously, we have demonstrated that atovaquone (ATV), an antimalarial, inhibits mitochondrial complex III E and restricts development cysts in vivo experiments. Therefore,...

AIM Cystic echinococcosis (CE) has potential economic effects to both animal products and human health. A vaccine to protect livestock against CE can be effective in reducing economic costs and increasing the livestock products. Protoscolex tegumental surface antigens (PSTSA) used to induce the production of specific antibodies against Echinococcus granulosus in sheep. The tegumental antigens w...

An 8-year-old child originally from Morocco spent 1 month in Spain before complaining of abdominal pain for the previous 24 hours. There was no fever, vomiting, or diarrhea. He had lived in a rural area with dogs and sheep. Physical examination detected a mass in upper-right abdominal area. Chest X-ray showed right hemidiaphragmatic elevation. Ultrasonography showed a hypoechoic cyst mass of 12...