نتایج جستجو برای: prune
تعداد نتایج: 2684 فیلتر نتایج به سال:
PRUNE is a member of the DHH (Asp-His-His) phosphoesterase protein superfamily of molecules important for cell motility, and implicated in cancer progression. Here we investigated multiple families from Oman, India, Iran and Italy with individuals affected by a new autosomal recessive neurodevelopmental and degenerative disorder in which the cardinal features include primary microcephaly and pr...
A 45-year-old man without relevant family history presented with prune belly syndrome (PBS). He had a 34year history of right simple partial motor seizures with and without secondary generalization, with a good response to carbamazepine monotherapy; there was no cognitive or social impairment. MRI showed global brain atrophy, ventricular asymmetry, left hemisphere schizencephaly, and bihemisphe...
Nm23-H1 is one of the most interesting candidate genes for a relevant role in Neuroblastoma pathogenesis. H-Prune is the most characterized Nm23-H1 binding partner, and its overexpression has been shown in different human cancers. Our study focuses on the role of the Nm23-H1/h-Prune protein complex in Neuroblastoma. Using NMR spectroscopy, we performed a conformational analysis of the h-Prune C...
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