PURPOSE To present a prospective, nonrandomized study of intraocular pressure (IOP) after clear corneal phacoemulsification in eyes with pseudoexfoliation (PEX) syndrome. METHODS A PEX group of 39 consecutive open angle, nonglaucomatous eyes with cataract in PEX syndrome, and a control group of 40 consecutive open angle, nonglaucomatous eyes with cataract, were operated on by the same surgeon...

Botling Taube, A. 2015. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1130. 54 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9312-7. Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fib...

Purpose: The objective of this study was to investigate the total antioxidant status (TAS) and DNA damage markers of serum and aqueous humor in patients with pseudoexfoliation (PEX) syndrome. Methods: Twenty-seven cataract patients with PEX and twenty-seven without PEX syndrome were included in the study and groups were matched for age and gender. Patients had no elevated intraocular pressure (...

Introduction/Objective Pseudoexfoliation syndrome (PEX) is an age-related systemic disorder characterized by deposition of fibrillary white flaky material mainly on the lens capsule, corneal endothelium, zonules, ciliary body, iris, and pupillary margin. Zonular weakness progressively increases along with the hardness of the lens, patient’s age, and the presence of glaucoma. The objective of th...

An 86-year-old man with a Binkhorst 2-loop intraocular lens (IOL) that was implanted in the pupillary sphincter 33 years earlier was examined. The pupil of the implanted eye with the Binkhorst IOL was irregular and the eye had pseudoexfoliation (PEX) syndrome. Pupillary erosion resulted from rubbing of the IOL edge against the pupillary sphincter with PEX material. The IOL was removed because o...

PURPOSE Evidence suggests that chronically increased stress conditions in the anterior eye segment constitute major mechanisms involved in the pathobiology of pseudoexfoliation (PEX) syndrome. The expression of stress-related genes in eyes from patients with and without PEX syndrome/glaucoma was investigated to determine whether PEX syndrome is associated with an altered cellular stress respons...

PURPOSE To determine the role of the extracellular chaperone clusterin in the pathophysiology of pseudoexfoliation (PEX) syndrome/glaucoma, which is characterized by the stable deposition of abnormal extracellular fibrillar material in anterior segment tissues. METHODS Real-time PCR, in situ hybridization, and immunohistochemistry were applied to analyze the mRNA and protein expression of clu...

OBJECTIVE To evaluate the corneal endothelial morphometry and central corneal thickness (CCT) in pseudoexfoliative (PEX) eyes with and without glaucoma and to compare with normal eyes and eyes with primary open-angle glaucoma (POAG). METHOD A total of 166 patients were included in this study: 36 eyes with pseudoexfoliation syndrome (PXS), 30 eyes with pseudoexfoliation glaucoma (PXG), 40 eyes...

OBJECTIVES To evaluate the anterior segment biometric features and corneal endothelial changes in eyes with pseudoexfoliation (PEX) syndrome and senile cataract. MATERIALS AND METHODS The central corneal thickness, anterior chamber depth (ACD), pupil diameter, lens thickness, endothelial cell density (ECD), and percentages of polymegathism and pleomorphism of 52 subjects with PEX and cataract...

AIM To evaluate the effect of torsional mode phacoemulsification on central corneal thickness, corneal endothelial cell density, and morphology in eyes with/without pseudoexfoliation (PEX) syndrome. METHODS Fourty-two consecutive patients with and 42 patients without PEX as a control group scheduled for cataract surgery was studied. Phacoemulsification, using OZiL IP system, was performed wit...