Background: Pseudomonas aeruginosa biofilm is one of the problems in antibiotic treatment infections. Nanomedicines, such as chitosan (CS) can carry multiple drugs and improve therapeutic effects antibiotics. Objectives: This study aimed at synthesis characterization ciprofloxacin-loaded nanoparticles for eradication P. aeroginosa biofilm. Methods: Cipro-CS microparticles were prepared by ionic...

BACKGROUND One of the main problems in the treatment of cases of P. aeruginosa especially in the orthopedic infections is the occurrence of high antibiotic resistance. The present study was carried out in order to investigate the prevalence of vancomycin-resistant P. aeruginosa in the cases of trauma in Iran. METHODS Two hundred and fifty swab samples were collected from the site of trauma fr...

The antimicrobial activity of the methanol extracts of the dried flowering aerial parts of Stachys byzantina, S. inflata, S. lavandulifolia and S. laxa (Labiatae) were studied using the disc diffusion method and determination of minimum inhibitory concentration (MIC) values against Staphylococcus aureus, Streptococcus sanguis, Escherichia coli, Pseudomonas aeroginosa, Klebsiella pneumoniae, Asp...

The investigation was conducted with methanolic extract of Murraya koenigii L for its anti bacterial, phytochemical screening and antioxidant capacities. Antibacterial activity of the extract was evaluated against various Grampositive and Gram-negative bacteria using agar well diffusion technique. For phytocehmical screening such as flavonoids. alkaloids, resins, glycosides, tannins, saponins, ...

Background Colistin-resistant Pseudomonas aeruginosa (P. aeruginosa) has been defined as pandrug-resistant (PDR) strain. Outbreaks of PDR P. aeruginosa especially in pulmonary tract infections due to contaminated bronchoscopes have rarely been reported. The emergence of pandrug-resistant strains in both CF (Cystic Fibrosis) and non-CF clinical isolates over recent years remains of a great conce...

In an attempt to study the biological activities of flavonoids, a flavone, flavanone and series of chalcones were synthesized and characterized by IR and 1 H NMR and elemental analysis. All the targeted compounds were screened for their antibacterial activity against Bacillus cereus, Enterococcus faecalis, Kleibsiella pneumonia and Pseudomonas aeroginosa and antifungal activity against Aspergil...

Background: Gastronomic natural flavors and spices have been used as both flavoring agents preservatives in food preparation for many years. They also utilized medical field their biological properties shown previous studies. Objective: The study aimed to evaluate the inhibitory effect of oil extracts from Cloves, Thyme, Cinnamon compared with ampicillin on some oral bacteria (Staphylococcus au...

two case reports of malignant external otitis in the elderly diabetics and their complications and management with regard to our experience at amir alam hospital, department of ent will be discussed here.