enucleation at different ages on the sizes of neurons in the lateral geniculate nucleus of infant and adult monkeys. Brain Res 1987;428:259–65. 6 Yücel YH, Kalichman MW, Mizisin AP, et al. Histomorphometric analysis of optic nerve changes in experimental glaucoma. J Glaucoma 1999;8:38–45. 7 Harwerth RS, Crawford MLJ, Frishman LJ, et al. Visual field defects and neural losses from experimental g...

1. The lateral geniculate nucleus is the primary thalamic relay for the transfer of retinal signals to the visual cortex. Geniculate cells are heavily innervated from nonretinal sources, and these modify retinogeniculate transmission. A major ascending projection to the lateral geniculate nucleus arises from cholinergic cells in the parabrachial region of the brain stem. This is an important pa...

To study the projection from the pretectum to the lateral geniculate nucleus, we placed wheat-germ agglutinin conjugated to horseradish peroxidase into the lateral geniculate nuclei of six cats, allowed this marker to be retrogradely transported by afferent axons to their parent somata in the pretectum, and revealed the label in these cells with stabilized tetramethylbenzidine histochemistry. I...

The cortical afferents from individual laminae of the dorsal lateral geniculate nucleus (LGN) were studied using both light and electron microscope autoradiography. In area 17, the A geniculate laminae (A and A1) had two main bands of projection, one extending from the bottom of IVc to the deepest cells in layer III, and one in layer VI. The C geniculate laminae projected in two dense bands to ...

The additivity assumption relates to the various stereo-disparity components in the vertical and horizontal meridians, each of which is assumed to be independent of the other, with the total disparity in each dimension being the linear sum of the separate components. Information about the position of the eyes provided by the corollary discharge leads to compensatory changes in the lateral genic...

Reticular facilitation of evoked responses in the lateral geniculate nucleus and visual cortex elicited by ipsilateral optic tract stimulation was studied in cats prepared under &ethyl ether-oxygen anesthesia, subsequently locally anesthetized, paralyzed with decamethonium, and placed on artificial respiration. In animals with an intact visual system, single electrical shocks to the reticular f...

We investigated the source of axons and terminals in the cat's lateral geniculate nucleus that stain positively for NADPH-diaphorase. The functional significance of such staining is that NADPH-diaphorase is identical to the enzyme nitric oxide synthetase, and thus it is thought to reveal cells and axons that use nitric oxide as a neuromodulator. Within the lateral geniculate and adjacent perige...

Five lagged cells were recognized by extracellular recording in the lateral geniculate nucleus of an awake, behaving macaque monkey. Previous reports of lagged cells were all in the anesthetized cat. Both parvocellular and magnocellular lagged cells were observed. Response timing was distributed continuously across the population, and both sustained and transient responses were seen in the magn...

Like the retinal ganglion cells from which they receive their input, most relay neurons in the lateral geniculate nucleus have ON- or OFF-center receptive fields with antagonistic surrounds. In the cat, neurons with these two types of receptive fields are anatomically intermingled, even though the ON and OFF systems are functionally segregated. In the ferret, there is a sublamination of the ret...