BACKGROUND Statistical methods that use the mid-p approach are useful tools to analyze categorical data, particularly for small and moderate sample sizes. Mid-p tests strike a balance between overly conservative exact methods and asymptotic methods that frequently violate the nominal level. Here, we examine a mid-p version of the McNemar exact conditional test for the analysis of paired binomia...

A Chlamydomonas reinhardtii mutant lacking CGL71, a thylakoid membrane protein previously shown to be involved in photosystem I (PSI) accumulation, exhibited photosensitivity and highly reduced abundance of PSI under photoheterotrophic conditions. Remarkably, the PSI content of this mutant declined to nearly undetectable levels under dark, oxic conditions, demonstrating that reduced PSI accumul...

The paper introduces the structure of parsimonious Portfolio Single Index (PSI) multivariate conditional and stochastic constant correlation volatility models, and methods for estimation of the underlying parameters. These multivariate estimates of volatility can be used for more accurate portfolio and risk management, to enable efficient forecasting of Value-at-Risk (VaR) thresholds, and to de...

In this paper, we first provide several conditional limit theorems for Lévy processes with negative drift and regularly varying tail. Then apply them to study the asymptotic behavior of expectations some exponential functionals heavy-tailed processes. As key point, observe that mainly depends on sample paths early arrival large jump. Both polynomial decay rate exact expression coefficients are ...

In cluster-specific studies, ordinary logistic regression and conditional for binary outcomes provide maximum likelihood estimator (MLE) (CMLE), respectively. this paper, we show that CMLE is approaching to MLE asymptotically when each individual data point replicated infinitely many times. Our theoretical derivation based on the observation a term appearing in average log-likelihood function c...

To understand the interplay between environmental stochasticity and Allee effects, we analyse persistence, asymptotic extinction, and conditional persistence for stochastic difference equations. Our analysis reveals that persistence requires that the geometric mean of fitness at low densities is greater than one. When this geometric mean is less than one, asymptotic extinction occurs with high ...