psoriasis is a chronic, non-contagious skin condition characterized by inflamed and scaly lesions of skin. whilst the pathogenesis of psoriasis is not known, psychological stress has been implicated as a potential trigger in the onset and exacerbation of the condition. psychiatric and psychological factors play an important role in at least 30% of dermatologic disorder and pathophysiologic link...

objective(s):psoriasis is an autoimmune disease that appears on the skin. although psoriasis is clinically and histologically well characterized, its pathogenesis is unknown in detail. the aims of this study were to evaluate the proteome of psoriatic patients' sera and to compare them with those of normal healthy human to find valuable biomarkers. materials and methods: in a case-control s...

Background: Psoriasis is a chronic inflammatory disease of theskin. The etiology of psoriasis is not known exactly. Recently, ithas been suggested that an imbalance in the oxidant- antioxidantstatus due to an increased reactive oxygen species production and/or deficient function of the antioxidant system may be involvedin the pathogenesis of psoriasis. The aim of this study was toevaluate the a...

Psoriasis is quite common in childhood, although congenital psoriasis is very rare. Here, we report a 2-year-old girl with typical linear psoriasis associated with bilateral hypopigmentation of breasts which has been present since birth.  

a central role for t cells and their cytokines in the pathogenesis of psoriasis has been proposed; however, there are controversies over the details of this issue. the goal of this study is to summarise currently available data on the importance of t cells in psoriasis pathogenesis. a  systematic  review  of  the  english  medical  literature  was  conducted  by  searching pubmed, embase, isi w...

Psoriasis is a common inflammatory, hyperproliferative skin disorder that affects 1% to 2% of the world population. The clinical diagnosis of psoriasis is relatively easy, especially when the lesions consist of erythematous, silvery white scaly, sharply demarcated, indurated plaques. Psoriasis is a chronic dermatosis of genetic origin, often precipitated by an event such as an infection, an inj...

BACKGROUND Psoriasis is associated with an atherogenic lipid profile but longitudinal changes in lipids around disease onset are unknown. The purpose of our study is to examine the effect of psoriasis onset on serum lipid profiles. METHODS We compared changes in lipid profiles in a population based incident cohort of 689 patients with psoriasis and 717 non-psoriasis subjects. All lipid measur...

abstract background: psoriasis is a chronic proliferative condition of the skin. its accurate pathogenesis has not been known yet, but interactions between genes and environmental factors have been implicated in its initiation. the role of malassezia in psoriasis is still undetermined, but several reports have associated these lipophilic yeasts with the development of skin lesions in psoriasis....

BACKGROUND Psoriasis is an immunoinflammatory disease associated with cardiovascular risk factors, atherothrombotic events, and hypercoagulability. Venous thromboembolism (VTE) is potentially lethal and shares risk factors with psoriasis, but the risk of VTE associated with psoriasis is unknown. The present study investigated the potential association between psoriasis and VTE. METHODS AND FI...