BACKGROUND Mental disorders, common in primary care, are often associated with physical complaints. While exposure to psychosocial stressors and development or presence of principal mental disorders (i.e. depression, anxiety and somatoform disorders defined as multisomatoforme disorders) is commonly correlated, temporal association remains unproven. The study explores the onset of such disorder...

The role of energy imbalance versus psychosocial stress in the pathogenesis of female reproductive dysfunction characterized by anovulation and amenorrhea remains controversial. In women, functional hypothalamic amenorrhea can develop in the absence of significant weight loss, excessive exercise, or profound psychosocial disruption. We posited, therefore, that commonplace, seemingly minor stres...

OBJECTIVES Aim was to examine the relationship between individually perceived changes in psychosocial stressors associated with German reunification and cardiovascular effects. We hypothesised that higher levels of psychosocial stress related to German reunification were associated with an increase in cardiovascular risk factors and cardiovascular diseases (CVDs). DESIGN Cross-sectional data ...

Chronic inflammation is a potentially important pathway through which psychosocial stressors increase risk for cardiovascular disease. However, prior research on stress and inflammation has been conducted almost exclusively in high income, industrialized populations with low levels of infectious disease. In this study we test the hypothesis that psychosocial stressors are associated with elevat...

Despite the fact that there is an extensive scientific literature regarding the importance of exposure to psychosocial stressors, the assessment of such stressors is often neglected in clinical work. The present review summarizes the scientific literature on critical life changes and work-related stressors. Particular emphasis has been on somatic outcomes and physiological processes that have b...

Background: Medical education throughout the world poses the incoming student with many challenging situations and demands. This forms an ideal environment for the student to be under stress as he/she adapts to these stress-inducing conditions. Factors both psychosocial and otherwise, vary widely between institutions of learning, the demographic studied, the external influences of the environme...

BACKGROUND Psychosocial stress may account for the higher prevalence of depression in women and in individuals with a low educational background. The aim of this study was to analyse the association between depression and socio-demographic data, psychosocial stressors and lifestyle circumstances from a gender perspective in a relatively affluent primary care setting. METHODS Patients, aged 18...

BACKGROUND Psychosocial job stressors, such as low control and high demands, have been found to influence the health and wellbeing of doctors. However, past research in this area has relied on cross-sectional data, which limits causal inferences about the influence of psychosocial job stressors on health. In this study, we examine this relationship longitudinally while also assessing whether th...

This paper describes the use of a mixed methods design to develop the Sri Lankan Children’s Daily Stressor Scale (CDSS). It brie£y describes its use in a study assessing the relative contribution of daily stressors on the one hand, and war and disaster exposure on the other, to young people’s mental health and psychosocial wellbeing.The authors discuss the neglect of daily stressors; the stress...

Chronic inflammatory diseases (autoimmunity, allergy and inflammatory bowel diseases) are increasing in prevalence in urban communities in high-income countries. One important factor is reduced exposure to immunoregulation-inducing macro- and microorganisms and microbiota that accompanied mammalian evolution (the hygiene hypothesis or 'Old Friends' mechanism). Reduced exposure to these organism...