Co-infections have been widely described in COVID-19 patients. Bacterial infections being the main cause but also reported fungal up to 20 % of cases. Candida species are second most common fungi identified pulmonary mycotic affecting hospitalized patients after Aspergillus. We present a case severe associated with candidiasis.

Cryptococcus neoformans is an environmental fungus that causes pulmonary and central nervous system infections. It also responsible for 15% of AIDS-related deaths.

Background: To investigate the value of metagenomic next-generation sequencing (mNGS) in diagnosis focal pulmonary infections by using radial ultrasound bronchoscopic “cocktail” specimens.