Background & Aims: Tuberculosis is one of the most important causes of mortality in the world and if it is not treated, 50 – 65% of patients would die in five years. Chest X-ray has an important role in the diagnosis of TB and early diagnosis and treatment prevent tuberculosis transmission. In this study we evaluated radiologic manifestations of patients with smear positive pulmonary tubercu...

we report a rare case of base of tongue tuberculosis following pulmonary tuberculosis. patient presented to us with chief complaints of sore throat and pain on swallowing for period of 3 months. on examination with 70 degree telescope, we observed an ulcer on right side of base of tongue. the edges of the ulcer appeared to be undermined with whitish slough at the centre of the ulcer. examinatio...

Background: Molecular detection has recently been proposed by nucleic acid amplification, known as polymerase chain reaction (PCR). The aim of this study was to compare the diagnostic method of smear and polymerase chain reaction with culture in terms of sensitivity, specificity, positive and negative predictive value in the diagnosis of pulmonary tuberculosis. Methods: In this cross-sectional...

co-infection of tuberculosis and leishmaniasis has been reported previously in patients with altered immune response due to primary or secondary immunodeficiency. these intracellular pathogens have a unique interaction in the host immune response and their development depends on impaired cell-mediated immunity. a case of chronic non-healing cutaneous ulcer with chronic fistulating soft-tissue m...

background and objectives: tuberculosis (tb) is a major problem in the world. treatment and control of tb needs detection of the mycobacterium tuberculosis (mt) in the proper samples. while smear doesn’t have enough sensitivity, culture and pcr are expensive, time consuming and unavailable in many centers. recent development of a rapid tb antigen detection test (prtbk) at pasteur institute of i...

the ratio of cd4+/cd8+ has been used as a clinically index to evaluate patients' immunity. numerous researchers have studied cd4+/cd8+ ratio in pulmonary tuberculosis (ptb) patients. however, the change of cd4+/cd8+ ratio remains controversial. we present a meta-analysis of 15 case-control studies to identify the change of cd4+/cd8+ ratio in ptb patients.we assessed heterogeneity of effect esti...

background: tuberculosis (tb) is still a major cause of morbidity and mortality in both developed and developing countries. delay in accessing tuberculosis care is associated with the highest densities of mycobacterium tuberculosis (m. tuberculosis) bacilli on sputum smears. objectives: the current study aimed to determine the extent of delay, and the major health system contributing factors to...

tuberculosis (tb) is an important health problem in developing countries, with varying clinical presentations depending on the organs/systems involved. to study the spectrum of clinical and paraclinical aspects of extra pulmonary tb in children suffering from pulmonary tb. this study has been carried out on 65 children with tuberculosis, admitted in tb wards of national research institute of tu...