In the olfactory bulb, odor representations by principal mitral cells are modulated by local inhibitory circuits. While dendrodendritic synapses between mitral and granule cells are typically thought to be a major source of this modulation, the contributions of other inhibitory neurons remain unclear. Here we demonstrate the functional properties of olfactory bulb parvalbumin-expressing interne...

Neocortical pyramidal cells (PYRs) receive synaptic inputs from many types of GABAergic interneurons. Connections between parvalbumin (PV)-positive, fast-spiking interneurons ("PV cells") and PYRs are characterized by perisomatic synapses and high-amplitude, short-latency IPSCs. Here, we present novel methods to study the functional influence of PV cells on layer 5 PYRs using optogenetics combi...

Plakophilin-1 (PKP-1) is an armadillo family protein critical for desmosomal adhesion and epidermal integrity. In the autoimmune skin-blistering disease pemphigus vulgaris (PV), autoantibodies (IgG) target the desmosomal cadherin desmoglein 3 (Dsg3) and compromise keratinocyte cell-cell adhesion. Here, we report that enhanced expression of PKP-1 protects keratinocytes from PV IgG-induced loss o...

PURPOSE Plasmalemmal vesicle associated protein-1 (PV-1) is up-regulated in the endothelium of human glioblastoma. We sought to further characterize the expression pattern of PV-1 in human brain tumors and interrogate its role in brain tumor angiogenesis. EXPERIMENTAL DESIGN Quantitative reverse transcription-PCR and in situ hybridization were used to measure PV-1 expression in a panel of 46 ...

Both circuit and single-cell properties contribute to network rhythms. In vitro, pyramidal cells exhibit theta-band membrane potential (subthreshold) resonance, but whether and how subthreshold resonance translates into spiking resonance in freely behaving animals is unknown. Here, we used optogenetic activation to trigger spiking in pyramidal cells or parvalbumin immunoreactive interneurons (P...

Parvalbumin-positive (PV+) fast-spiking basket cells are thought to play key roles in network functions related to precise time keeping during behaviorally relevant hippocampal synchronous oscillations. Although they express relatively few receptors for neuromodulators, the highly abundant and functionally important neuropeptide cholecystokinin (CCK) is able to selectively depolarize PV+ basket...

This paper presents modeling and simulation for the PV cells, modules, and array, and building of blocks based on MATLAB / Simulink software package. The main aim of this work is the improvement of the PV solar cell simulator based on a two-diode model. This model is more accurate than the single diode model especially at low insolation levels; therefore this will gives more accurate prediction...

This paper shows a circuit to emulate the operation of a photovoltaic (PV) cell. The values of equation is based on data sheet in the Standard Condition Measurement (SCM), this model allows emulate PV cell, including effects due to variations of irradiance receiver and temperature of cell. The generic model is the same for all types of PV cells, only can used the same equations including variab...

A view of contemporary systems and control challenges in PV cell manufacturing is given in this paper, with emphasis on developing a modeling strategy for the optimization of thin-film silicon nitride SiNx:H films used for passivation and anti-reflection coatings in single (sc-) and multicrystalline silicon (mc-Si) solar cells. The overall framework integrates three modeling modules: a remote p...

Replication of poliovirus (PV) is restricted to a few sites, including the brain and spinal cord. However, this neurotropism is not conserved in cultured cells. Monkey kidney cells become susceptible to PV infection after cultivation in vitro, and cell lines of monolayer cultures from almost any tissue of primates are susceptible to PV infection. These observations suggest that cellular changes...