Objectives: To evaluate the validity of ultrasound for diagnosis and exclusion of pyloric stenosis in the infants with nonbilious vomiting. Methodology: In a cross-sectional study, 444 consecutive infants with clinical suspicion of pyloric stenosis were evaluated by ultrasound (US) and categorized as pyloric stenosis or not according measuring parameters as muscle thickness, muscle width and ca...

Four studies reported an increasing incidence of pyloric stenosis during the late 1970s from geographically diverse areas of the United Kingdom. It was suggested that the increased incidence might be related to changes in infant feeding practices. We used data from the Metropolitan Atlanta Congenital Defects Program, a population based birth defects registry, to examine the secular trends and d...

CONTEXT Pyloric stenosis is the most common condition requiring surgery in the first months of life. Case reports have suggested familial aggregation, but to what extent this is caused by common environment or inheritance is unknown. OBJECTIVES To investigate familial aggregation of pyloric stenosis from monozygotic twins to fourth-generation relatives according to sex and maternal and patern...

The neuropeptide, red pigment concentrating hormone (RPCH), strengthened the inhibitory synapse from the lateral pyloric (LP) neuron to the pyloric dilator (PD) neurons in the pyloric network of the stomatogastric ganglion (STG) of the lobster, Homarus americanus. RPCH produced several-fold increases in the amplitude of both action potential-mediated and non-impulse-mediated transmission that p...

Pyloric atresia is a congenital anomaly manifested by gastric outlet obstruction. The radiographic signs are characterised by the presence of the gas-bubble sign, the pyloric dimple sign and the absence of the beak sign. The differential diagnosis of these signs is discussed in view of other gastric outlet obstructions. Ultrasonography is of value in demonstrating the absence of the normal echo...

1. A long-lasting restructuring of the pyloric neural network of the lobster stomatogastric nervous system (STS) by a multisynaptic sensory afferent is described. This restructuring can be obtained either by mechanical stimulation of the pyloric region of the stomach or by brief high-frequency electrical stimulation of a nerve that innervates this region, the lateral posterolateral nerve (lpln)...

We examined the dopamine (DA) modulation of calcium currents (ICa) that could contribute to the plasticity of the pyloric network in the lobster stomatogastric ganglion. Pyloric somata were voltage-clamped under conditions designed to block voltage-gated Na+, K+, and H currents. Depolarizing steps from -60 mV generated voltage-dependent, inward currents that appeared to originate in electrotoni...

Simple, primary, or idiopathic hypertrophy of the pyloric muscle in the adult resembles the congenital pyloric hypertrophy of infants, and no associated lesion, such as a peptic ulcer, is apparent. The hypertrophy, which narrows and elongates the pyloric canal, is limited to the muscle of the pyloric sphincter and, most commonly, mainly involves the circular muscle; sometimes it is focal. The c...

............................................................................................................. ii Acknowledgements ............................................................................................ v Table of contents ............................................................................................... vi List of figures ..........................................

BACKGROUND Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of gastric outlet obstruction in infants. This study was conducted to identify the accuracy of ultrasonography in the diagnosis of infantile Hypertrophic pyloric Stenosis. METHODS This cross-sectional descriptive study was conducted in Department of Paediatric Surgery, Children Hospital Complex & the Institute of Chil...