نتایج جستجو برای: quantitative magnetization transfer imaging qmti

تعداد نتایج: 1039931  

Journal: :AJNR. American journal of neuroradiology 2016
R Zivadinov B Raj M Ramanathan B Teter J Durfee M G Dwyer N Bergsland C Kolb D Hojnacki R H Benedict B Weinstock-Guttman

BACKGROUND AND PURPOSE The effect of comorbidities on disease severity in MS has not been extensively characterized. We determined the association of comorbidities with MR imaging disease severity outcomes in MS. MATERIALS AND METHODS Demographic and clinical history of 9 autoimmune comorbidities confirmed by retrospective chart review and quantitative MR imaging data were obtained in 815 pat...

Journal: :Brain : a journal of neurology 2014
Hugh Kearney Marios C Yiannakas Rebecca S Samson Claudia A M Wheeler-Kingshott Olga Ciccarelli David H Miller

Neuropathological studies in multiple sclerosis have suggested that meningeal inflammation in the brain may be linked to disease progression. Inflammation in the spinal cord meninges has been associated with axonal loss, a pathological substrate for disability. Quantitative magnetic resonance imaging facilitates the investigation of spinal cord microstructure by approximating histopathological ...

Journal: :Archives of neurology 2008
Zhaleh Khaleeli Daniel R Altmann Mara Cercignani Olga Ciccarelli David H Miller Alan J Thompson

BACKGROUND Magnetization transfer imaging has the potential to provide a surrogate marker for progression in primary progressive multiple sclerosis (PPMS). OBJECTIVES To investigate whether brain magnetization transfer imaging, T2 lesion load, and atrophy changes over 3 years reflect concurrent clinical changes, and which baseline imaging measure best predicts progression over 3 years in earl...

Journal: :Neurology 1997
S E Kasner S L Galetta J C McGowan R I Grossman

We report a patient with biopsy-proven progressive multifocal leukoencephalopathy (PML) who was serially imaged with MRI and magnetization transfer imaging. The magnetization transfer ratio (MTR) was profoundly and significantly diminished when compared with normal control subjects. The pattern of MTR was distinct from that of MS and periventricular ischemic white matter disease. Magnetization ...

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