One new and six known flavone glycosides were isolated from the MeOH extract of Melilotus neapolitana Ten. The new compound, identified as 7-O-beta-D-glucopyranosyloxy-4',5-dihydroxy-3-[O-alpha-L-rhamnopyranosyl-(1-->6)-3-O-beta-D-glucopyranosyloxy]flavone (1) by 1D and 2D NMR techniques and mass spectra, was isolated along with kaempferol-3-O-rutinoside (2), kaempferol-3-O-glucoside (3), rutin...

Many previous investigations have found quercetin to be a powerful antioxidant and antitumor flavonoid, but its poor bioavailability has limited use. This current study investigated the effects of two newly synthesized Quercetin Schiff bases containing 2-amino thiadiazole-5-thiol (Q1), benzyl derivatives (Q2) on MCF-7 human breast cancer cells. Cell viability apoptosis were assessed determine t...

This study examined the effects of a combination soybean fiber and α-glycosyl-isoquercitrin (AGIQ) on improving quercetin bioavailability glucose metabolism in rats fed an obesogenic diet. For 9 weeks, were individually control diet, high-fat high-sucrose (H) H with (HS), or AGIQ (HQ), both (HSQ). Quercetin derivatives plasma, feces, urine, cecal content quantified by high-performance liquid ch...

A purification and fractionation process of the edible flowers Tibouchina mollis urvilleana followed by first attempt to anthocyanin flavonol characterisation identification UHPLC-DAD-ESI-MS were developed. T. exhibited a higher monomeric content, mainly due presence 3-O-(6′-p-coumaroyl)-glucoside derivatives malvidin petunidin. Quercetin-3-O-hexoside was major identified in urvilleana, lack my...

Major brands of cocoa powder products present in the Spanish market were analyzed for monomeric flavanols [(+)-catechin and (-)-epicatechin] and flavonols [quercetin-3-glucuronide, quercetin-3-glucoside (isoquercitrin), quercetin-3-arabinoside, and quercetin]. In addition, the influence of the manufacturing process of cocoa powder products, in particular, the alkalinization treatment ( Dutching...

A specific objective of this paper was to evaluate seasonal changes in bioactive compounds level (carotenoids and polyphenols) in juice prepared from organic and non-organic tomatoes in Poland. In the examined tomato juice, the content of dry matter, vitamin C, carotenoids as well as polyphenols (by HPLC method) has been measured. The presented results indicate the impact of the growing system ...

Natural flavonoids such as quercetin, (+)catechin and rutin as well as four methoxylated derivatives of quercetin used as models were investigated to elucidate their impact on the oxidant and antioxidant status of human red blood cells (RBCs). The impact of these compounds against metal toxicity was studied as well as their antiradical activities with DPPH assay. Antihemolytic experiments were ...

Flavonoids are polyphenolic secondary metabolites from plants that possess a common phenylbenzopyrone structure (C6-C3-C6). Depending upon variations in their heterocyclic C-ring, flavonoids are categorised into one of the following groups: flavones, flavonols, flavanones, flavanols, anthocyanidins, isoflavones or chalcones. Flavonols include, among others, the molecules quercetin, myricetin an...