نتایج جستجو برای: rab23

تعداد نتایج: 78  

Journal: :Brain research reviews 2008
Ee Ling Ng Bor Luen Tang

The Rab family of small GTPases serves as cellular regulators of vesicular transport in all eukaryotes. Higher organisms have a vastly expanded number of Rabs. Some of these would presumably perform cell-type or tissue-specific functions. Roles for Rab proteins in several aspects of cellular physiology that are peculiar to neurons have been revealed. Rabs, in conjunction with their effectors an...

Journal: :The Journal of Cell Biology 2007
Adam C. Smith Won Do Heo Virginie Braun Xiuju Jiang Chloe Macrae James E. Casanova Marci A. Scidmore Sergio Grinstein Tobias Meyer John H. Brumell

Members of the Rab guanosine triphosphatase (GTPase) family are key regulators of membrane traffic. Here we examined the association of 48 Rabs with model phagosomes containing a non-invasive mutant of Salmonella enterica serovar Typhimurium (S. Typhimurium). This mutant traffics to lysosomes and allowed us to determine which Rabs localize to a maturing phagosome. In total, 18 Rabs associated w...

Journal: :Genetics 2016
Ibrahim Ömer Çiçek Samir Karaca Marko Brankatschk Suzanne Eaton Henning Urlaub Halyna R Shcherbata

Since the discovery of microRNAs (miRNAs) only two decades ago, they have emerged as an essential component of the gene regulatory machinery. miRNAs have seemingly paradoxical features: a single miRNA is able to simultaneously target hundreds of genes, while its presence is mostly dispensable for animal viability under normal conditions. It is known that miRNAs act as stress response factors; h...

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