Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the t...

OBJECTIVES The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. MATERIALS AND METHODS Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the thor...

OBJECTIVE To observe the effect of tonifying Kidney herbs (TKH) in pituitary, ovary, adrenal gland of androgen sterilized rats(ASR). METHODS ASR model was established by injecting testosterone propionate subcutaneously to SD female rats of 9 days age. Morphological and hormonal change of pituitary, ovary and adrenal gland in rats of 100-107 days old before and after feeding TKH extract were o...

FUKUCHI, S., TAKENOUCHI, T. and NAIKAJTSA, K. Effect of Furosemide Administration and Upright Position on Plasma Renin Activity and Angootensin ‡U in Hypertension. Tohoku J. exp. Med., 1973, 111 (1), 71-78 Both plasma renin activity and angiotensin ‡U during recumbency measured by radioimmuno assay, were normal in essential hypertension, chronic glomerulonephritis and bilateral renal artery ste...

AIM To measure the intracolonic release of nitric oxide end products (nitrates plus nitrites) and eicosanoids in response to intraluminal irritation with deoxycholic acid (DCA). PATIENTS Seven patients with irritable bowel syndrome. METHODS The left colon was perfused with a solution with or without 3 mM deoxycholic acid. Aspirates were assayed for eicosanoids by specific radioimmuno-assay,...

The isolation, chemical nature, and biological activity of the new iron compound ferrichrome have been reported elsewhere (l-3). Biochemical interest in ferrichrome centers, at present, around (a) its growth factor activity for PiZobolusl and (b) its possible relationship to cytochrome c formation in Ustilago sphaerogena. A suitable assay method for ferrichrome has been much desired as an aid t...

THE USUAL METHOD of peptide estimation requires the assay of a protein-free filtrate for amino-acid concentration before and after hydrolysis. Peptide amino acid is then calculated by difference (1). In another method (2) specifically designed for urine, the peptides are precipitated with phosphotungstic acid from a trichloroacetic acid filtrate. The precipitate is dissolved and color is formed...

In traditional practice medicine, plants are used in many countries to control diabetes mellitus. The hypoglycaemic actions of these medicinal plants are beings studied. Fenugreek (Trigonella foenum graecum) has been documented as a traditional treatment of diabetes. In the present study, oral administration of alcoholic fenugreek extract (0.1, 0.25, 0.5 g/kg body wt.) and glibenclamide (600 mg...