The widespread adoption of on-board volumetric imaging in cancer radiotherapy has stimulated research efforts to develop online adaptive radiotherapy techniques to handle the inter-fraction variation of the patient's geometry. Such efforts face major technical challenges to perform treatment planning in real time. To overcome this challenge, we are developing a supercomputing online re-planning...

Introduction: According to the literature, optical coherence tomography (OCT) can be used measure radiation absorbed dose. This study was carried out to design a computed tomography system for the calculation of absorbed dose and optimization of dose delivery in radiotherapy using gel dosimeters. Material and Methods: An advanced charge-coupled device based OCT system was developed in laborator...

Background: The motions of body and tumor in some regions such as chest during radiotherapy treatments are one of the major concerns protecting normal tissues against high doses. By using real-time radiotherapy technique, it is possible to increase the accuracy of delivered dose to the tumor region by means of tracing markers on the body of patients.Objective: This study evaluates the accuracy ...

Aim: To prospectively evaluate the acute toxicity of 3D conformal radiotherapy with dose optimization in patients with carcinoma cervix. Materials and Methods: Carcinoma cervix patients stage IIB to IIIB (n = 30) treated during November 2011 to May 2013 at the institution with 3D conformal chemo-radiation were included in the study. They received weekly Cisplatin 40 mg/m2 for a maximum of 5 cyc...

The optimization of a Fuzzy Cognitive Map model for the supervision and monitoring of the radiotherapy process is proposed. This is performed through the minimization of the corresponding objective function by using the Particle Swarm Optimization and the Differential Evolution algorithms. The proposed approach determines the cause–effect relationships among the concepts of the supervisor–Fuzzy...

Electron beam radiotherapy is the most widespread treatment modality todeal with superficial cancers. In electron radiotherapy, energy spectrum isimportant for modelling and accurate dose calculation. Since thepercentage depth-dose (PDD) a function of beam’s energy, reconstruction from curve represents an inverse problem.Thus, can be related to by means anappropriate mathematical model as Fredh...