We show the phenomenon of complete synchronization in an network of coupled oscillators. We confirm that non-diagonal coupling can lead to the appearance or disappearance of synchronous windows (ragged synchronizability phenomenon) in the coupling parameter space. We also show the appearance of clusters (synchronization in one or more group) between coupled systems. Our numerical studies are co...

Chronic progressive external ophthalmoplegia (CPEO) is a rare clinical syndrome characterized by slowly progressive paralysis of extraocular muscles. We report a male patient who had a 20 year history of CPEO. Histological examination of left deltoid muscle showed characteristic ragged red fibers. Electron microscopy revealed a number of abnormal mitochondria which contain paracrystalline inclu...

ragged edge not fixed to the underlying tissues, it is fairly deep, is covered with a dirty looking necrotic slough or scab, and though not painful it is tender. The surrounding skin gets discoloured, infiltrated, inflamed and markedly cedematous, there is some lymphangitis and sometimes phlebitis. There may be a general malaise and slight evening rise of temperature owing to secondary infection.

BACKGROUND Mitochondrial diseases are caused by mutations in mitochondrial or nuclear genes, or both and most patients do not present with easily recognizable disorders. The characteristic morphologic change in muscle biopsy, ragged-red fibers (RRFs) provides an important clue to the diagnosis. MATERIALS AND METHODS Demographic data, presenting symptoms, neurological features, and investigati...