نتایج جستجو برای: raji cell line
تعداد نتایج: 1969438 فیلتر نتایج به سال:
The HLA-D locus in the major histocompatibility complex controls the expression of the genetically polymorphic HLA-DR antigens. mRNA coding for the beta chains of these antigens was partially purified from the human lymphoblastoid cell line Raji. The mRNA was copied into double-stranded cDNA and cloned in Escherichia coli. One clone, pDR-beta-1, obtained by hybrid selection, carries a 1070-base...
background: cd19 is a pan b cell marker that is recognized as an attractive target for antibody-based therapy of b-cell disorders including autoimmune disease and hematological malignancies. the object of this study was to stably express the human cd19 antigen in the murine nih-3t3 cell line aimed to be used as an immunogen in our future study. methods: total rna was extracted from raji cells i...
A T cell line from mononuclear cells in the synovial fluid of a patient with polyarthritis was established. The T cell line reacted with serum samples positive for antibodies to human T cell lymphotropic virus type I (HTLV-I) and with monoclonal antibody to HTLV-I p19. In Southern blotting with an env-pX-LTR HTLV-I probe and digestion of T cell line DNA with the restriction enzymes ClaI, DraI, ...
background: prostate cancer is one of the leading causes of cancer deaths among men. new gene expressed in prostate (ngep), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. because of its selective expression in prostate cancer cell surface, ngep is a potential immunotherapeutic target. to target the ngep in prostate cancer, it is essential to investigat...
OBJECTIVE To investigate the effects of Artesunate (ART) on the Raji cell proliferation, apoptosis and autophagy with Raji cells of Burkitt's lymphoma as the objects of study, and to investigate the anti-tumor mechanism of ART. MATERIALS AND METHODS Morphological examinations of apoptotic and autophagy were performed. MTT assay was used to detect the cell proliferation after ART treatment. Th...
RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer.
shiga toxins (stxs) are bacterial virulence factors produced by shigella dysenteriae serotype 1 and escherichia coli strains. stxs are critical factors for the development of diseases such as severe bloody diarrhea and hemolytic uremic syndrome. additionally, stxs trigger the secretion of pro- inflammatory cytokines and chemokines, particularly in monocytes or macrophages. the inflammatory cyto...
زمینه و هدف: ساخت و ترکیب داروهای جدید گیاهی و شیمیایی علیه بیماری هایی مثل سرطان، از جمله تلاش های مهم سال های اخیر محسوب می شود. ترکیبات ترپنی از جمله ترکیبات مهمی هستند که خواص بیولوژیکی و فارماکولوژیکی متعددی دارند، اما به دلیل حلالیت کم آن ها در محلول های آبی کمتر مورد توجه بوده اند. سیکلودکسترین ها نیز نانوکپسول های طبیعی تشکیل شده از واحدهای گلوکزی هستند که می توانند ایجاد نانوحفره نماین...
Measles virus (MV) has a very limited host range, humans being the only natural reservoir of the virus. This restriction may be due to the absence of an MV receptor on the surface of non-primate cells. We have studied the MV-binding ability of several cell lines and attempted to characterize the receptor by studying the binding of 35S-labelled MV and by a rosette formation technique. We confirm...
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