introduction: endothelial cells are subjected to mechanical forces caused by pulsatile flow and pressure leading to hemodynamic shear stress and circumferential stress on endothelial layer. the study aimed at a quantitative evaluation of endothelial cell morphology by application of cyclic loading. endothelial cells respond to applied loads with adaptation and remodeling. such mechanisms are ma...

Fatigue damage is traditionally determined from time signals of loading, usually in the form of stress or strain. This approach is satisfactory for periodic loading but requires very large time records to accurately describe random loading processes. These may prove prohibitive for many finite element analyses especially when modelling dynamic resonance. Alternatively, a compact frequency domai...