نتایج جستجو برای: rational design

تعداد نتایج: 1015307  

Journal: :British Journal of Pharmacology 2007

Journal: :IEEE Trans. Systems, Man, and Cybernetics, Part A 1998
Gregory E. Kersten Sunil J. Noronha

Several studies of two-party negotiations have shown that negotiators more often than not reach inefficient compromises. We analyze the circumstances under which rational agents make inefficient compromises and refrain from improving them. We do this by describing and interpreting various negotiation situations and by developing formal constructs and theorems for determining the character of a ...

Journal: :Int. J. Game Theory 2007
Zafer Akin

1. The Problem and Related Literature In our daily lives, we always face decisions to make and alternative actions to choose overtime. Traditional economic analysis expects people behave rationally (take actions maximizing their payoff or utility) and thus behave consistently (following the original contingent plan or strategy) when they make these decisions. In other words, a rational agent's ...

2011
Arne Laks̊a Børre Bang Lubomir T. Dechevsky A. Laks̊a B. Bang L. T. Dechevsky

This is the first one in a sequence of several papers dedicated to the development of applications of Euler Beta-function B-splines (BFBS) to Computer-aided Geometric Design (CAGD) and, in particular, for geometric modelling of parametric curves, surfaces and volume deformations. This study is an analogue of the study conducted in [12, 10] for the case of expo-rational Bsplines (ERBS). An impor...

2008
Frederick W. B. Li

Parametric surface [Fari02] is a surface defined by a tensor-product of parametric curves, which are represented by parametric equations. As such surface comes with a well defined mathematical definition, it becomes one of the most common geometric tools for computer-aided geometric design and object modeling aids for many computer graphics applications. Typical examples of such surface include...

1992
Tomoyuki Nishita Shinichi Takita Eihachiro Nakamae

Shaded display is popular for displaying curved surfaces because of the realistic appearance of the images produced. In the eld of computer aided geometric design, however, line drawings are more commonly used. For accurate evaluation of the curved surfaces in these designs, the conventional method of approximating curved surfaces with polygons is insu cient. In this paper we will present a met...

2015
April L. Ellis Jenny J. Yang David Wilson Giovanni Gadda Vincent Rehder Charles Louis

Understanding the temporal and spatial changes in calcium concentration has been a difficult endeavor for many years due to the relatively small changes in calcium concentration during messenging events, the rapid changes upon physiological messenging, and the unavailability of fast, efficient, and sensitive sensors to detect calcium changes. In addition, the key factors in calcium binding have...

Journal: :Angewandte Chemie 2006
Udo Feldkamp Christof M Niemeyer

DNA has many physical and chemical properties that make it a powerful material for molecular constructions at the nanometer length scale. In particular, its ability to form duplexes and other secondary structures through predictable nucleotide-sequence-directed hybridization allows for the design of programmable structural motifs which can self-assemble to form large supramolecular arrays, scaf...

2016

Drug design may be considered as an integrated whole approach which essentially involves various steps, namely : chemical synthesis, evaluation for activity-spectrum, toxicological studies, metabolism of the drug, i.e., biotransformation and the study of the various metabolites formed, assay procedures, and lastly galenical formulation and biopharmaceutics. The ‘drug design’ in a broader sense ...

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