conclusions sch is associated with increased level of pla2-iia, which is independent of bmi. the stronger association of sch with pla2-iia than with hs-crp indicates that pla2-iia is an inducer of inflammation while hs-crp is not. results serum levels of tg, cholesterol, and ldl were higher in the sch group than the control group. however, there was no significant difference between the two gro...

background: macrophage immune responses are affected by the secretory proteins of mycobacterium tuberculosis (mtb). this study aimed to examine the immune responses of macrophages to mtb secretory antigens, namely esat-6, cfp-10, and esat-6/cfp-10. methods: thp-1 cells (a human monocytic cell line) were cultured and differentiated to macrophages by phorbol 12-myristate 13-acetate. the cytotoxic...

recent studies show that, inflammation plays an important role in the initiation and progression of atherosclerosis and in the pathogenesis of acute cardiovascular events. there is a possible association between ventricular dysfunction following acute myocardial infarction and high sensitivity c-reactive protein (hs-crp) and uric acid. in this study we assessed the relationship between hs-crp a...

background: polycystic ovary syndrome (pcos), a common endocrine disorder, is associated with infertility, menstrual dysfunction, hirsutism and frequent miscarriages. insulin resistance, as a major cause of pcos, represents a disorder with increase in inflammatory markers and risk of type 2 diabetes. we aimed to investigate whether inflammatory markers, including c-reactive protein and c3 (comp...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

conclusions while the crp value was in patients with acute brucellosis in the current study, the mpv, rdw and leukocyte counts were within the normal range. crp value remains the most valuable inflammatory marker in cases of acute brucellosis. results the follow-up within the year after treatment was examined. the values of age, gender, leukocyte count, c-reactive protein, rdw and mpv were reco...

background: several factors are associated with the development or exacerbation of pain in knee osteoarthritis (koa). in this study, we reviewed this context based on relevant studies. methods: recent published studies which have addressed the relationship between pain and koa were summarized. results: correlates of the clinical, demographic features, laboratory tests and abnormalities on radio...

background: psoriasis is a chronic and inflammatory dermatologic disease. inflammatory biomarkers such as c-reactive protein (crp) and erythrocyte sedimentation rate (esr) are known as immediate and delayed inflammatory biomarkers, respectively. due to the fact that anti-inflammatory drugs such as infliximab are widely used in psoriasis treatment, the aim of this study was to evaluate esr, crp ...