BACKGROUND The antipyretic effectiveness of rectal versus oral acetaminophen is not well established. This study is designed to compare the antipyretic effectiveness of two rectal acetaminophen doses (15 mg/kg) and (35 mg/kg), to the standard oral dose of 15 mg/kg. METHODS This is a randomized, double-dummy, double-blind study of 51 febrile children, receiving one of three regimens of a singl...

The purpose of this study is to examine risk factors for late rectal toxicity for localized prostate cancer patients treated with helical tomotherapy (HT). The patient cohort of this retrospective study was composed of 241 patients treated with HT and followed up regularly. Toxicity levels were scored according to the Radiation Therapy Oncology Group grading scale. The clinical and dosimetric p...

PURPOSE To demonstrate the feasibility of transperineal polyethylene glycol (PEG) hydrogel insertion into anterior perirectal fat for reducing rectal radiation dose in patients with suboptimal rectal dosimetry after permanent iodine-125 prostate brachytherapy. METHODS AND MATERIALS Five patients with suboptimal rectal dosimetry after iodine-125 seed brachytherapy implant underwent a single tr...

This study aims to provide the means for testicular dose estimation from radiotherapy for rectal cancer. Rectal irradiation was simulated on a humanoid phantom using a 6 MV photon beam. The effect of field size, distance from irradiated area, wedge introduction into lateral beams, tissue thickness along the beam axis and use of gonad shields on the testicular dose was examined. Testicular dose ...

Rationale: Rectal diazepam (0.5 mg/kg-maximum single dose 20 mg) is our standard practice for terminating prolonged (seizure > 5 minutes and continuing) or acute repetitive seizures in children, both inpatient and at home. Recently, clinically significant respiratory depression, requiring mechanical support has been reported in 8.8% of children receiving rectal diazepam (Norris et al, Dev. Med....

introduction: study the protective effect of mucosal bcg vaccination with subcutaneous against leishmania major infection in susceptible balb/c mice material and methods: 6-8 weeks old male balb/c mice,were divided to two test groups and four control groups of 20 of mice and then vaccinated. two test groups vaccinated with appropriate dose of bcg through rectal and subcutaneous routs. they vacc...

BACKGROUND MOSFET dosimetry is a method that has been used to measure in-vivo doses during brachytherapy treatments and during linac based radiotherapy treatment. Rectal displacement devices (RDDs) allow for safe dose escalation for prostate cancer treatment. This study used dual MOSkin detectors to assess real-time in vivo rectal wall dose in patients with an RDD in place during a high dose pr...

PURPOSE The dose values computed with the treatment planning system and the in vivo dose measurements with semiconductor detectors in rectum during the high dose rate brachytherapy treatment fraction of the cervix carcinoma are occasionally significantly different. We've investigated the consistency of the Fletcher-Suit applicator geometry and the in vivo rectal probe's position stability durin...

PURPOSE To describe chronic rectal mucosal damage after pelvic radiotherapy (RT) for cervical cancer and correlate these findings with clinical symptoms and radiation dose. MATERIALS AND METHODS Thirty-two patients who underwent pelvic RT were diagnosed with radiation-induced proctitis based on endoscopy findings. The median follow-up period was 35 months after external beam radiotherapy (EBR...

The purpose of this study was to determine the risk factors for rectal bleeding after prostate brachytherapy. Between April 2005 and September 2009, 89 patients with T1c-2cN0M0 prostate cancer were treated with permanent I-125 seed implantation alone. The prostate prescription dose was 145 Gy, and the grade of rectal bleeding was scored according to the Common Terminology Criteria for Adverse E...