BACKGROUND Recurrent radiation-induced osteosarcoma of the sternum following remote radiation therapy for breast cancer and sternal reconstruction. CASE A 51-year-old woman presents with recurrent, radiation-induced sternal osteosarcoma 11 years after receiving both radiation therapy for breast cancer and sternal reconstruction. The case details both her work-up and subsequent course, includi...

Purpose:Tounderstand the role ofHER2-associated signalingnetwork inbreast cancer stemcells (BCSC) using radioresistant breast cancer cells and clinical recurrent breast cancers to evaluate HER2-targeted therapy as a tumor eliminating strategy for recurrent HER2 /low breast cancers. Experimental Design: HER2-expressing BCSCs (HER2þ/CD44þ/CD24 ) were isolated from radiation-treated breast cancer ...

background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...

background: inflammatory breast cancer (ibc), a subgroup of locally advanced breast cancer (labc), is diagnosed based on clinical findings, and seems to be different from other types of labc. the purpose of this study was to compare clinicopathological characteristics and outcomes between inflammatory and non-inflammatory labc patients at breast cancer research center (bcrc), tehran, iran. meth...

INTRODUCTION Therapy comprising 5-fluorouracil, levofolinate, and oxaliplatin is currently the most common chemotherapy for colorectal cancer. We experienced a successful case of advanced colon cancer and recurrent breast cancer with 5-fluorouracil, levofolinate, and oxaliplatin therapy. CASE PRESENTATION A 43-year-old Japanese woman who had already undergone surgery three times for bilateral...

Purpose: To understand the role of HER2-associated signaling network in breast cancer stem cells (BCSCs); using radiation-resistant breast cancer cells and clinical recurrent breast cancers to evaluate HER2-targeted therapy as a tumor eliminating strategy for recurrent HER2 breast cancers. Experimental Design: HER2-expressing BCSCs (HER2/CD44/CD24) were isolated from radiation-treated breast ca...

breast conservation surgery combined with radiation therapy is now an accepted option for the treatment of early breast cancer. so we decided to evaluate the results of such treatment in our first group of patients treated by this method. from 1992 to 1996 , one hundred patients with stage i and ii breast cancer treated with breast conservative surgery (lumpectomy or quadrantectomy). were irrad...

nloaded report on the development of a monitoring test for recurrent breast cancer, using metaboliteng methods. Using a combination of nuclear magnetic resonance (NMR) and two-dimensional gas atography–mass spectrometry (GC×GC-MS) methods, we analyzed the metabolite profiles of 257 retrove serial serum samples from 56 previously diagnosed and surgically treated breast cancer patients. One ed si...

ownload report on the development of a monitoring test for recurrent breast cancer, using metaboliteng methods. Using a combination of nuclear magnetic resonance (NMR) and two-dimensional gas atography–mass spectrometry (GC×GC-MS) methods, we analyzed the metabolite profiles of 257 retrove serial serum samples from 56 previously diagnosed and surgically treated breast cancer patients. One ed si...

Downlo report on the development of a monitoring test for recurrent breast cancer, using metaboliteng methods. Using a combination of nuclear magnetic resonance (NMR) and two-dimensional gas atography–mass spectrometry (GC×GC-MS) methods, we analyzed the metabolite profiles of 257 retrove serial serum samples from 56 previously diagnosed and surgically treated breast cancer patients. One ed six...