The formal potentials of several redox couples incorporated in coatings of a perfluoropolycarboxylate on graphite electrodes were measured and compared with the formal potentials of the same couples in homogeneous solution. The differences observed agreed with those calculated from the Nernst equation with the independently measured incorporation coefficients for both halves of the redox couple...

Intracellular redox potential of skeletal muscle becomes progressively more oxidized with aging, negatively impacting regenerative ability. We examined the effects of oxidizing redox potential on terminal differentiation of cultured C2C12 myoblasts. Redox potentials were manipulated by changing the culture O(2) environment, by free radical scavenging, or addition of H(2)O(2.) Intracellular reac...

For many cytochromes P450 (P450), the electrons are transferred from the reductase to the P450 via a [2Fe-2S] cluster ferredoxin (e.g. putidaredoxin, terpredoxin or adrenodoxin). A similar role is played by several plant-type ferredoxins to transfer electrons from photosystem I to NADP. Other ferredoxins like E. coli ferredoxin are probably involved in the biogenesis of iron-sulfur clusters. To...

CONSPECTUS: All-atom methods treat solute and solvent at the same level of electronic structure theory and statistical mechanics. All-atom computation of acidity constants (pKa) and redox potentials is still a challenge. In this Account, we review such a method combining density functional theory based molecular dynamics (DFTMD) and free energy perturbation (FEP) methods. The key computational ...

To support investigations of flood tolerance occurring at a field-based research facility, changes in soil volumetric water content, temperature, redox potential, dissolved oxygen content, and pH over the course of flood events were monitored. Electronic sensors connected to dataloggers for continuous monitoring of these parameters were installed, and soil redox potential and pH were also monit...

Comparative study of electrochemical redox behaviour of five different nitroxyl radicals leads to the direct correlation between one-electron redox potentials and group electronegativity of the beta-substituent on the ring. Beta-substituents with an electron-donating effect caused a negative shift in the one-electron oxidation and one-electron reduction potentials of the nitroxyl radicals. In a...

The redox potentials have been determined for nine azaanthraquinones in phosphate buffer at pH 7.2 by means of cyclic voltammetry. A definite correlation has been found between the redox potentials and the inhibitory effects of the azaanthraquinones on Epstein-Barr virus early antigen (EBV-EA) activation. It has further been shown that the correlation can be made better by introducing an electr...

Density functional theory calculations have been performed to calculate the one-electron redox potential for a series of oxoiron(IV) porphyrin complexes of the form [(TMP)Fe(IV)(O)(L)] (TMP = 5,10,15,20-tetramesitylporphyrinate). Different axial ligands were chosen (L = none, Im, ClO4(-), CH3CO2(-), Cl(-), F(-), SCH3(-)) in order to compare the results with recent electrochemical experiments. T...

The reaction of the WO4(2-) ion in the pH range 2 to 8 was carried out with the following metal ions individually in combination: Mn2+, Mn3+, Fe2+, Fe3+, Co2+, Co3+, Ni2+, Cu1+, Cu2+, Zn2+, Ga3+, Mg2+, In3+, RAsO3(2-), RSbO3(2-). Some 36 heteropolyanions have been isolated in the crystalline form characterized fully. The antiviral activity of these anions has been determined against HIV, herpes...

The redox potentials of cobalt and iron complexes with ten pyridylazo compounds, E(0)(ML2) (ML(2)(+/0); M: Co(III/II), Fe(III/II); L(-): pyridylazo compounds), have been determined in order to explore the difference in their reversed-phase HPLC behavior. The redox potentials of Co complexes were in the range of -0.62 - 0.03 V, while those of Fe complexes were -0.06 - 0.59 V relative to 0.20 V f...