background: mesial temporal lobe epilepsy (tle) is a remediable epileptic syndrome. about 40% of patients continue to have seizures after standard temporal lobectomy. it has been suggested that some of these patients could actually suffer from a more complex epileptogenic network. because a few papers have been dedicated to this topic, we decided to write an article updating this theme. methods...

OBJECTIVE To compare the sensitivity of standard magnetic resonance imaging (MRI) scans done outside an epilepsy center with that of special protocol MRI scans done at an epilepsy center in delineating relevant lesions of the temporal lobe. SUBJECTS Eighty-four consecutive patients who had temporal lobe resections for refractory temporal lobe epilepsy between January 1, 1993, and February 1, ...

Temporal lobe epilepsy surgery has become a successful alternative in patients with refractory epilepsy. However, the outcome of epilepsy surgery may be affected by the occurrence of postsurgical psychiatric symptoms, such as psychosis. This report describes three cases of refractory temporal lobe epilepsy and hippocampal sclerosis, which, after anterior temporal lobectomy, presented with acute...

PURPOSE To determine the long-term efficacy of anterior temporal lobectomy for medically refractory temporal lobe epilepsy in patients with nonlesional magnetic resonance imaging (MRI). METHODS We identified a retrospective cohort of 44 patients with a nonlesional modern "seizure protocol" MRI who underwent anterior temporal lobectomy for treatment of medically refractory partial epilepsy. Po...

background epilepsy is a chronic neurological disease with the prevalence of around one percent. despite the introductions of several anti-epileptic drugs, around 1/3 of epileptic patients are resistant to the anti-epileptic medications. objectives considering the evidence regarding the anti-oxidant action of vitamin e and its beneficiary effect in the treatment of epilepsy, we investigated the...

Introduction Surgery for temporal lobe epilepsy is proven to be beneficial in the treatment of medically refractory temporal lobe epilepsy. Subdural electrode strips are commonly passed in a blind fashion, allowing additional EEG coverage without requiring larger exposure. However, this increases risk of complication, specifically through vascular injury. Case report We present a case of a 22...

introduction: kainic acid (ka) induces neuropathological changes in specific regions of the mouse hippocampus comparable to changes seen in patients with chronic temporal lobe epilepsy (tle). according to different studies, the expression of a number of genes are altered in the adult rat hippocampus after status epilepticus (se) induced by ka. this study aimed to quantitatively evaluate changes...

background: this study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) with those who have temporal lobe epilepsy (tle) due to other etiologies.   methods : in this retrospective study all patients with a clinical diagnosis of tle were recruited in a referral outpatient epilepsy clinic at shiraz university of medical scie...