Previous studies have reported the efficacy of baclofen in the treatment of Gastroesophageal Reflux Diseases (GERD). The objective of present study is to evaluate the effect of co-administration of omeprazole 20 mg/d plus sustained Release baclofen (SR baclofen) vs omeprazole 20 mg/d plus placebo on alleviation of symptoms in patients with a diagnosis of GERD. A prospective, double blind, place...

Background The quantification of valvular regurgitation by CMR is usually a second-line diagnostic tool that is used when echocardiography has proven inconclusive. According to guidelines are aortic and mitral regurgitations considered severe if the regurgitation volume > 60 ml and regurgitation fraction > 50 %. Regurgitation of a single heart valve may be calculated by comparing LVSV and RVSV ...

BACKGROUND Heartburn and regurgitation frequently occur in the third trimester of pregnancy, but their impact on quality of life has not been thoroughly investigated. OBJECTIVE To measure health-related quality of life of third-trimester pregnant women with heartburn and regurgitation. Methods Data on obstetric history, heartburn and regurgitation frequency and intensity, history of heartburn...

The case of a 73-year-old white man with corrected transposition of the great vessels and associated mitral and mild aortic regurgitation is reported. The patient's survival was the longest of any patient with this defect reported to date. Although the condition is theoretically compatible with a normal life span, few patients with this lesion survive past 40 years of age because of associated ...

background: longer survival after the total repair of the tetralogy of fallot increases the importance of late complications such as right ventricular dysfunction. this is a prospective study of the right ventricular function in totally corrected tetralogy of fallot patients versus healthy children. methods: thirty-two healthy children were prospectively compared with 30 totally corrected tetra...

The aim of the present study was to elucidate the mechanisms of mitral regurgitation accompanying myocardial infarction. Severity and site of mitral regurgitation was evaluated by the real-time two-dimensional Doppler flow imaging technique in 81 patients with old myocardial infarction. The incidence of mitral regurgitation did not depend on the region of infarction. There was, however, a close...

To assess the accuracy of echocardiography in determining the cause of aortic regurgitation M mode and cross sectional echocardiography were compared with angiography in 43 patients with predominant aortic regurgitation. Each patient had all three investigations performed during the same admission to hospital. In each instance, the cause of aortic regurgitation was confirmed at surgery or necro...

d a v p s a o Background. The importance of moderate ischemic itral regurgitation in patients presenting for coronary rtery bypass grafting (CABG) is controversial. Thereore, we tracked the course of unrepaired moderate schemic mitral regurgitation after CABG surgery alone, dentified factors associated with worsening postoperaive ischemic mitral regurgitation, and assessed the imact of unrepair...

Previous studies have reported the efficacy of baclofen in the treatment of Gastroesophageal Reflux Diseases (GERD). The objective of present study is to evaluate the effect of co-administration of omeprazole 20 mg/d plus sustained Release baclofen (SR baclofen) vs omeprazole 20 mg/d plus placebo on alleviation of symptoms in patients with a diagnosis of GERD. A prospective, double blind, place...