conclusions inhalation of tiotropium bromide in combination with pulmonary rehabilitation could improve some plethysmographic lung volumes and clinical outcomes in patients with chronic pulmonary disease due to sm. short-term prescription of pulmonary rehabilitation has no effect on cpet of patients. patients and methods in a randomized clinical trial, using convenient sampling method, 54 patie...

Prions are composed solely of an alternatively folded isoform of the prion protein (PrP), designated PrP(Sc). The polyoxometalate phosphotungstic acid has been used to separate PrP(Sc) from its precursor PrP(C) by selective precipitation; notably, native PrP(Sc) has not been solubilized by using nondenaturing detergents. Because of the similarities between PrP(Sc) and lipoproteins with respect ...

BACKGROUND Spontaneous sputum production occurs in a subset of COPD patients; however, its clinical relevance has not been established. Differences in health status and clinical outcomes between patients with and without positive sputum cultures are unknown. OBJECTIVE To compare clinical characteristics and health status of spontaneous sputum producers with a positive culture (SC+) and negati...

Sodium chlorite (SC) is an effective sanitizer for inhibiting microbial growth. This investigation was conducted to determine the efficacy of SC as a browning control agent for use on fresh-cut apple slices, applied alone, or in conjunction with organic acids. Additionally, the authors compared the efficacy of SC to that of acidified sodium chlorite (ASC) and to several other salts and examined...

INTRODUCTION The cardiac action potential (CAP) of stem cell-derived human cardiomyocytes (SC-hCMs) is potentially the most powerful preclinical biomarker for cardiac safety and efficacy in humans. Our experiments tested this hypothesis by examining the CAP and relevant pharmacology of these cells. METHODS The electrophysiological and pharmacological profiles of SC-hCMs were compared to rabbi...

introduction: parkinson s disease (pd) is a common progressive neurodegenerative disorder, which its onset is later in adults and it s incidence increases in people aged between 55 and 60 years. dexterity, because of it s role at upper extremity function and person independency in function, is assessed in rehabilitation. purdue- pegboard test often is used in rehabilitation clinical settings...

1 Brain Rehabilitation Research Center, Malcom Randall VA Medical Center, Gainesville, FL, USA 2 Department of Aging and Geriatric Research, University of Florida, Gainesville, FL, USA 3 Ralph H. Johnson VA Medical Center, Charleston, SC, USA 4 Department of Health Sciences and Research, Medical University of South Carolina, Charleston, SC, USA 5 Department of Applied Physiology and Kinesiology...

l-Dopa@MSNs based on the concept of drug-structure-directing agents were successfully prepared and proved to be programmed oral l-Dopa release nanosystem pH responsive for treatment Parkinson's disease.

Recently, we showed that L-arginine (L-Arg) supplementation could attenuate acute exercise-induced oxidative and inflammatory stress in aging rats. In this study, we investigate whether L-Arg supplementation protects cellular oxidative stress, inflammation, or the mitochondrial DNA 4834-bp large deletion (mtDNA4834 deletion) in 14-week-old young rats tissues during exhaustive exercise. Rats wer...