The evolution of reperfusion therapy in the treatment of acute myocardial infarction (AMI) has highlighted the extraordinary importance of rapid and accurate diagnosis of infarcts due to thrombosis of a major epicardial vessel, the so-called Q-Wave Myocardial Infarction or Transmural Myocardial Infarction. The presence of AMI can be established by a wide variety of diagnostic tests, but the nar...

The ideal non-invasive method for detecting coronary reperfusion has not yet been established. In 63 patients with acute myocardial infarction, serum myoglobin and creatine kinase-MB were measured every 15 min. Thrombolytic treatment was given (n = 52) and acute coronary angiography showed a patent infarct-related artery in 49 patients while 14 patients had no coronary reperfusion. Median time ...

BACKGROUND Coronary artery disease remains the principal cause of death in patients with diabetes mellitus. Diabetic mice display exacerbated injury following myocardial ischemia-reperfusion (MI/R) and are resistant to most therapeutic interventions. We have reported that sodium sulfide (Na2S) therapy confers cardioprotection during MI/R in non-diabetic mice. Here we tested the hypothesis that ...

Reperfusion therapy with intravenous thrombolysis or mechanical thrombectomy is effective in improving outcome for ischemic stroke but remains underused. Patients presenting of unknown onset are a common clinical scenario and reason not offering reperfusion therapy. Recent studies have demonstrated the efficacy time onset, when guided by advanced brain imaging. However, translation into practic...

The therapeutic efficacy of stem cell therapy in many diseased organs based greatly on their paracrine effect. neural cells are thought to have a role improving the neurological functional, recovery, and reduction cerebral infarction caused by ischemia/ reperfusion [I/R] injury rats.