background: sodium valproate, an anticonvulsant drug, is reported to stimulate human immunodeficiency virus type 1 and human cytomegalovirus replication. since epileptic patients undergoing sodium valproate therapy may suffer from various virus infections, the effect of this drug on replication of viruses especially those affecting neuronal tissues such as herpes simplex virus type 1 is worthy ...

a complication in the analysis of the role of icp34.5 gene in the herpes simplex virus type-1 (hsv-1) lifecycle is the presence of overlapping antisense gene, open reading frame p (orf p), which is also deleted in hsv-1 icp34.5 negative mutants. a hsv-1 wild type strain (17+) icp34.5/orf p deletion mutant (1716) is totally avirulent in animal models and impaired in a number of in vitro function...

Abstract— Data grids are an important branch of gird computing which provide mechanisms for the management of large volumes of distributed data. Energy efficiency has recently emerged as a hot topic in large distributed systems. The development of computing systems is traditionally focused on performance improvements driven by the demand of client's applications in scientific and business domai...

In data grid, using reservation is accepted to provide scheduling and service quality. Users need to have an access to the stored data in geographical environment, which can be solved by using replication, and an action taken to reach certainty. As a result, users are directed toward the nearest version to access information. The most important point is to know in which sites and distributed sy...

The genome of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) has an untranslated region (UTR) that enhances the replication and transcription RNA, subgenomic RNA (sgRNA) which encodes 4 structural proteins are essential for viral replication. host cell SARS CoV-2 expresses important enzyme called TMPRSS2 protease allows virus to invade cell. Peptide conjugated phosphorodiamidate m...