OBJECTIVE To outline the usefulness of videothoracoscopic and videoassisted surgery in the final staging, resectability evaluation and treatment of lung cancer, and its possible advantages over thoracotomy. PATIENTS AND METHOD Videothoracoscopy was performed on 296 patients suffering from lung cancer. Patient selection criteria are described, as well as techniques for the different kinds of r...

Hepatic resection has become the treatment of choice for metastatic colorectal cancer, and this technique increases five-year survival cancer patients up to 40–58%. More recently, criteria resectability have been revised expanded include any patient in whom all deposits can be removed with a negative surgical margin sufficient residual liver parenchyma. Currently, is determined mostly by minimu...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies with a 5-year survival rate of <7%. Carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) are often used to predict the outcome of the malignancy independently. However, the joint prognostic effect of the two tumor biomarkers has not been well determined. The study assessed the joint role of preoperat...

The incidence of intrahepatic cholangiocarcinoma (iCCA) is highest in Eastern countries, such as Thailand, South Korea, and China, but its mortality are increasing worldwide. Over recent decades, the worldwide age-standardized for iCCA has been steadily increasing, whereas that perihilar CCA distal decreasing. macroscopic growth pattern somewhat different according to anatomic location tumor. c...

Objectives The present study aimed to investigate the efficacy, toxicity, and impact of induction chemotherapy (IC) in technically unresectable T4a oral cavity squamous cell cancers (OSCCs). Materials and Methods Patients diagnosed with technically unresectable locally advanced T4a OSCC from January 2013 and November 2016 at our center, who received 2-3 cycles of IC and then assessed for rese...

BACKGROUND Pancreatic adenocarcinoma (PCA) is one of the most lethal human malignancies, and radical surgery remains the cornerstone of treatment. After resection, the overall 5-year survival rate is only 10% to 29%. At the time of presentation, however, about 40% of patients generally have distant metastases and another 40% are usually diagnosed with locally advanced cancers. The remaining 20%...

BACKGROUND To evaluate the predictors for resectability and survival of patients with locally advanced pancreatic cancer (LAPC) treated with gemcitabine-based neoadjuvant therapy (GBNAT). METHODS Between May 2003 and Dec 2009, 41 tissue-proved LAPC were treated with GBNAT. The location of pancreatic cancer in the head, body and tail was 17, 18 and 6 patients respectively. The treatment respon...