4 アブストラクト 我々の脳はネットワークである.脳は空間的に区分された構造で成り立っているが,お互いに連続的に情報の 共有をする領域間で機能的に結合している.興味深いことに,近年の脳機能イメージングデータ解析の発展によっ て,脳の機能的結合の調査が促進している.機能的結合は構造的に解離している領域の神経活動パターンの時間 的依存と定義され,脳領域間のレスティングステイト fMRIにおける協調した活動のレベルを計測することによっ て機能的結合の研究が増加してきた.これらの先行研究によって,特定領域と局所ネットワークの機能的結合に ついてや脳ネットワークにおける機能的連絡の全体的な構成についての新たな知見が発見された.本稿では,新 たな解析手法の紹介とこれらのイメージング技術の概要を提示しながら,人間の脳のコアとなる新たな見識がど のように導かれたのかを議論する.どのように脳ネットワー...

Hyperpolarization-activated cation currents, termed If, Ih, or Iq, were initially discovered in heart and nerve cells over 20 years ago. These currents contribute to a wide range of physiological functions, including cardiac and neuronal pacemaker activity, the setting of resting potentials, input conductance and length constants, and dendritic integration. The hyperpolarization-activated, cati...

In this work we propose taking noise into account when modeling the neuronal activity in a correlation-based type network. Volume transmission effects on connectivity are considered. As a result, an individual module can be set in an “activated” state via noise produced by the remaining modules. The stochastic approach could provide a new insight into the relation between functional and anatomi...

Using combined emotional stimuli, combining photos of faces and recording of voices, we investigated the neural dynamics of emotional judgment using scalp EEG recordings. Stimuli could be either combioned in a congruent, or a non-congruent way.. As many evidences show the major role of alpha in emotional processing, the alpha band was subjected to be analyzed. Analysis was performed by computin...

Networks of cortical neurons were grown over multi electrode arrays to enable simultaneous measurement of signals from multiple neurons. Functional connectivity in cultured networks has been described by relationships between individual electrodes, based on conditional firing probabilities. In this study we investigated periods in which the strength of a relationship increased (strengthening) o...