BACKGROUND Adding cetuximab to standard chemotherapy results in a moderate increase of overall survival in patients with advanced non-small-cell lung cancer (NSCLC), but the cost-effectiveness is unknown. MATERIALS AND METHODS A Markov model was constructed based on the results of the First-Line ErbituX in lung cancer randomized trial, adding cetuximab to cisplatin-vinorelbine first-line chem...

Using a data sample corresponding to an integrated luminosity of 0:35 fb 1 collected by LHCb in 2011, we report the first evidence of CP violation in the decays of Bs mesons to K pairs, ACPðBs ! K Þ 1⁄4 0:27 0:08ðstatÞ 0:02ðsystÞ, with a significance of 3:3 . Furthermore, we report the most precise measurement of CP violation in the decays of B mesons to K pairs, ACPðB ! K Þ 1⁄4 0:088 0:011ðsta...

However, by this time the treatment had had its most successful period and in 1952 the first drug with a definite effect on schizophrenia was introduced, chlorpromazine, our first neuroleptic drug. Since about 1960 lobotomy, with a strongly modified technique (more discrete incisions), has been used only when there are very special indications such as in severe anxiety, and compulsive syndromes...

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We investigate the static potential in the confinement phase of the SU(2) Higgs model on the lattice, where this model is expected to have properties similar to QCD. We observe that Wilson loops are inadequate to determine the potential at large distances, where the formation of two color-neutral mesons is expected. Introducing smeared fields and a suitable matrix correlation function, we are a...

The present paper examined the relationship of population to the environment and with growing population, poverty and urbanization the environment is degrading. Conducted an analysis of changes and trends over last fifty years. The study reveals that the country's population growth is imposing an increasing burden on the country's limited and continually degrading natural resource base. The nat...