Background: People with Axial Spondyloarthritis (axSpA) experience a diagnostic delay between 7 to 10 years. (1-5) This contributes increased depression and desperation in searching for an appropriate diagnosis. (6) Consequently, people axSpA impaired physical function, structural damage, overall worsened quality of life than those who timely (7) Objectives: To gain knowledge understand patient...

Background: A recent study examining Commercial Claims Insurance database found that many patients with ankylosing spondylitis (AS) do not remain on their initial TNF inhibitor two years after initiation, particularly women and those taking opioids. Objectives: To examine factors associated switching from one (i)agent to either another TNFi, IL-17i or JAKi over time (at <2years >2 years) ...

Background: Human leukocyte antigen-B27 (HLA-B27) is found in most patients (pts) with ankylosing spondylitis (AS). Although a subset of pts AS are HLA-B27 negative (NEG), ensuring treatment efficacy this subpopulation important. Objectives: This analysis evaluated the ixekizumab (IXE), high-affinity monoclonal antibody selectively targeting interleukin-17A, who either positive (POS) or NEG. Me...

Background Comorbidities in ankylosing spondylitis (AS) occur more frequently than the general population and are associated with higher morbidity mortality. Some comorbidities may together, making one likely presence of another, different combinations have differential considerations for AS management outcomes. Objectives To examine association baseline disease activity functional status AS. M...

is more common among the dicots than the monocots (Renner and Ricklefs, 1995). Dioecy is a breeding system that promotes cross-pollination in Poa is a large, diverse genus that belongs to the subplants. The transfer of this trait into economically important selfpollinated cereal crops would revolutionize the production of hybrids family Pooideae of the Poaceae. Several species are in these spec...

Objective. Systemic sclerosis (SSc) affects multiple physical, psychological, and social domains and is associated with impaired health-related quality of life (HRQOL).We compared the HRQOL of SSc patients with individuals in the general population and patients with other common chronic diseases. Methods. HRQOL of SSc patients in the Canadian Scleroderma Research Group registry was measured usi...

1 Presenter: Donghai Wen Authors: Donghai Wen, Bangchen Wang, Ryan Cornelius, Yang Yuan, Huaqing Li2 Jun Wang-France, and Steven Sansom Title: A Micropuncture Study of the Net K Secretion in the Thick Ascending Limb of Mice on a Low Na High K Diet Abstract: Understanding the effect of a cardioand reno-protective low Na high K diet (LNaHK) on renal K handling is crucial to choosing diuretics and...