background: patients with rheumatoid arthritis (ra) suffer from wide ranges of autoimmune reactions in joints. the mechanism of which is generally unknown and maybe associated with treg deregulation. objective: to compare the frequency of ntregs in peripheral blood of patients with active rheumatoid disease with healthy individuals. methods: twenty five newly diagnosed patients with active ra d...

the purpose of this study was to investigate any association between iga deficiency (igad) and juvenile rheumatoid arthritis (jra) among iranian children. this case-control study was carried out on 83 children who were diagnosed as jra according to american college of rheumatology (acr) criteria; patients were admitted at the rheumatology clinic of children's medical center, (tehran). serum imm...

background rheumatoid arthritis (ra) is a chronic inflammatory disease with extra- articular involvement. eyes in particular are one of the most common sites of involvement in rheumatoid arthritis. on the other hand, dry eye syndrome is the most common conflict in terms of management. particular studies suggested dry eye has been associated with greater rheumatoid arthritis severity, but its as...

objectives: foot and ankle problems are common complications in rheumatoid arthritis disease. gait pattern such as normal foot and ankle rocker is impaired in patients with rheumatoid arthritis. rocker sole as an external shoe modification is commonly prescribed in this pathology. the aim of this study was to investigate the effect of rocker shoe on vertical ground reaction force parameters dur...

rheumatoid factors (rf) are autoantibodies with specificity for the fc portion of human igg. production of rf is a characteristic feature of rheumatoid arthritis (ra) and is detectable in high titer in about 90% of these patients. in this study, we measured total igm, iga, igmrf and igarf in serum and synovial fluid of 45 ra patients by elisa and the results were compared with those obtained by...

background and objectives: the cause and pathophysiology of rheumatoid arthritis has not been fully understood and an experimental model of this disease is essential for research on the problem. in this research study, establishment and histopathological changes of chronic arthritis due to intra-articular antigen injection was used as a model of experimental rheumatoid arthritis. materials and ...