Abstract Rhinoscleroma is a chronic infectious condition found mainly in patients living underdeveloped regions. It affects the respiratory tract (in 95% of cases nasal cavity first affected), but it can also involve orbit, middle ear, lip, gums and cutaneous tissue. linked to infection with Klebsiella rhinoscleromatis. Females are far more frequently affected than males. Symptoms typically app...

Rhinoscleroma is a chronic granulomatous infection of the upper respiratory tract, particularly affecting the nose. It is a bacterial disease mainly caused by rhinoscleromatis subspecies of Klebsiella pneumoniae. We described a case of a 72-year-old Chinese man presented with repeated epistaxis for more than 2 years without any inducing factors accompanied by nasal obstruction, purulent dischar...

Rhinoscleroma is a chronic, granulomatous infectious lesion most frequently affecting the respiratory tract mucosa. This disease is endemic to Africa, Central and South America, South Central and Eastern Europe, the Middle East, and China. We report an extremely rare disease of nasal rhinoscleroma in Korea. The patient was a 63-yr-old man, who suffered from chronic nasal obstruction and septal ...

We tested in vitro the activities of streptomycin and tetracycline--antibiotics that have long been used to treat rhinoscleroma--as well as several newer oral agents by using 23 isolates of the causative organism Klebsiella rhinoscleromatis. All isolates were inhibited by clinically achievable concentrations of trimethoprim-sulfamethoxazole, amoxicillin-clavulanate, chloramphenicol, ciprofloxac...

Rhinoscleroma is a chronic inflammatory disease in which granulation tissue with a typical cell content is found. The paper presents the case of a 77-year-old woman with clinically diagnosed nodule in the nasal cavity. The histopathological examination revealed granulation tissue with plasma cells and Mikulicz's cells. The clinical and morphological picture of the case in question is a rare opp...