abstract background autologus platelet gel is easy to prepare and is relatively low cost. the aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. materials and methods in this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. thrombin was prepared by mixing the plasma with calcium. thrombin activity lev...

OBJECTIVE To investigate whether the cartilage regenerative effects of intra-aricular platelet-rich plasma (PRP) are different, according to the severity of osteoarthritis (OA), in a collagenase-induced knee OA rabbit model. METHOD New Zealand white rabbits (N=21) were randomly divided into three groups. Three different doses (0.25 mg, group 1; 0.5 mg, group 2; and 1.0 mg, group 3) of collage...

blood transfusion centers are under considerable pressure to produce platelet concentrates with high quality and safety due to the short shelf life of 3-5 days as well as possible bacterial and viral contaminations. for a variety of reasons, many europeans have changed their methods of component production from whole blood using the north american standard platelet-rich plasma method to the buf...

background the platelet-rich plasma (prp) and hyaluronic acid (ha) constitute a system of tissue growth that can regenerate damaged tissue. this study was performed to evaluate the effect of prp and ha in treatment of complications of achilles tendon reconstruction. methods we selected ten patients affected by achilles tendon injuries resulting from post-surgical complications subsequent to ten...

background clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. the aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (prp) injection in healing achilles tendons of rats. methods forty rats were randomly divided into 5 equal groups. sevent...

background:the utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (ppp). this effect is largely mediated by the increased or decreased concentration of platelets in the plasma. the current study aimed to analyze and evaluate the impact of platelet-rich (...

Study design and methods: A Medline search with keywords ‘platelet rich plasma dental’ further filtered using Boolean operators (AND, Or, NOt) and combination of specific keywords as follows: ‘platelet rich fibrin’, ‘platelet rich plasma regenerative’, ‘platelet rich plasma periodontal’, ‘platelet rich plasma extraction’ with a custom range of 10 years was performed, which yielded 88 results ou...

BACKGROUND Autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. Tendinopathies are common in clinical practice, although long-term treatment is required. On the basis of lead time, we compared the effect of using platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in repairing rat Achilles tendon. METHODS The effectiveness of usi...

BACKGROUND The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect. METHODS We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen mat...