Ionic liquid crystals combine the unique solvent properties of ionic liquids with self-organization found for liquid crystals. We report a detailed analysis of the structure-property relationship of a series of new imidazolium-based liquid crystals with an extended aromatic core. Investigated parameters include length and nature of the tails, the length of the rigid core, the lateral substituti...

In this paper, we study the following new variant of prototype learning, called k-prototype learning problem for 3D rigid structures: Given a set of 3D rigid structures, find a set of k rigid structures so that each of them is a prototype for a cluster of the given rigid structures and the total cost (or dissimilarity) is minimized. Prototype learning is a core problem in machine learning and h...

An ideal I on a cardinal κ is called rigid if all automorphisms of P (κ)/I are trivial. An ideal is called μ-minimal if whenever G ⊆ P (κ)/I is generic and X ∈ P (μ)V [G] \ V , it follows that V [X] = V [G]. We prove that the existence of a rigid saturated μ-minimal ideal on μ+, where μ is a regular cardinal, is consistent relative to the existence of large cardinals. The existence of such an i...

An efficient, solvent free method for the N-arylation of imidazole by 1-(dodecyloxy)-4-iodobenzene using Cu(II)-NaY as catalyst and K(2)CO(3) as base is reported. By this synthetic approach, mesomorphic 3-[4-(dodecyloxy)phenyl]-1-methyl-1H-imidazol-3-ium iodide was synthesized in a two-step procedure, and its mesomorphism has been fully investigated by polarised optical microscopy, differential...

The [Het-s] prion of the fungus Podospora anserina represents a good model system for studying the structure-function relationship in amyloid proteins because a high resolution solid-state NMR structure of the amyloid prion form of the HET-s prion forming domain (PFD) is available. The HET-s PFD adopts a specific β-solenoid fold with two rungs of β-strands delimiting a triangular hydrophobic co...

Programmed cell death 5 (PDCD5) protein is phylogenetically conserved in both the nucleus and cytoplasm. The human PDCD5 protein is expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli, and recently it was found that PDCD5 is an important regulator in both apoptotic and non-apoptotic programmed cell death. In this study, human PDCD5 was expressed in Escherichi...

Motivated by recent efforts to mitigate blast loading using energy-absorbing materials, this paper investigates the uniaxial crushing of cellular media in sandwich construction under impulsive pressure loading. The cellular core is modeled using a rigid, perfectly-plastic, locking idealization, as in previous studies, and the front and back faces are modeled as rigid, with pressure loading appl...

Fibrils from the Parkinson's-disease-related A53T mutant of alpha-synuclein were investigated by solid-state NMR spectroscopy, electron microscopy, and atomic force microscopy. Sequential solid-state NMR resonance assignments were obtained for a large fraction of the fibril core. Experiments conducted above and below the freezing point suggest that the fibrils contain regions with increased mob...

objective(s): chalcones and their rigid analogues represent an important class of small molecules having anticancer activities. therefore, in this study the synthesis and cytotoxic activity of new 3-benzylidenchroman-4-ones were described as rigid chalcone analogues.   materials and methods: the reaction of resorcinol with 3-chloropropionic acid in the presence of cf3so3h was afforded correspon...

Image registration is an important enabling technology in medical image analysis. The current emphasis is on development and validation of application-specific non-rigid techniques, but there is already a plethora of techniques and terminology in use. In this paper we discuss the current state of the art of non-rigid registration to put on-going research in context and to highlight current and ...