The acute oral toxicity of the anticoagulant rodenticide diphacinone was found to be about 20 times greater to American kestrels (LD50=97 mg/kg) than to northern bobwhite (LD50=2,014 mg/kg). Several precise and sensitive clotting assays (prothrombin time, Russell’s Viper venom time, thrombin clotting time) were adapted for use in these species, and this combination of assays is recommended to d...

The utility and characteristics of the family of anticoagulant rodenticides are reviewed, including the new members difenacoum, bromadiolone and brodifacoum. General considerations are given in investigating the likelihood of nontarget poisoning with rodenticides. The literature dealing with secondary poisoning studies and concerns with the use of anticoagulant rodenticides is reviewed. The uti...

Warfarin, zinc phosphide, norbormide and alphachloralose have been microencapsulated by the technique of coacervation and fed to laboratory rats (R. norvegicus) and mice (M. musculus). Results are given of experiments in which the concentration of rodenticide, wall material and phase ratio have been varied separately and in combination. Experiments are also reported in which normal and encapsul...

Fluoroacetamide is a high effective rodenticide with broad spectrum. A series of toxic symptoms emerge such as nausea, vomiting with bloody vomitus, epigastric burning, dizziness, headache, fatigue, face muscle twitching, dysphoria, expiratory dyspnea, hypotension, recurrent epigastric burning, general paroxysmal and tonic convulsion. Fluoroacetamide toxic leukodystrophy was rarely reported. He...

Rodenticides have historically been common agents in attempted suicides. As most rodenticides in the United States (U.S.) are superwarfarins, these ingestions are generally managed conservatively with close monitoring for coagulopathy, and if necessary, correction of any resulting coagulopathy. However, alternate forms of rodenticides are imported illegally into the U.S. and may be ingested eit...

Cases of rodenticide poisoning (second-generation long-acting dicoumarin rodenticide, superwarfarin) have occasionally been reported. The main symptoms of bromadiolone poisoning are skin mucosa hemorrhage, digestive tract hemorrhage, and hematuresis. However, the symptoms of central nervous system toxicity have rarely been reported. Our case reports on a 41-year-old male who had no contact with...

aluminum phosphide (alp) is a highly effective rodenticide which is used as a suicide poison. herein, a 24 year-old man who’d intentionally ingested about 1liter of alcohol and one tablet of alp is reported. acute myocardial infarction due to alp poisoning has been occurred secondary to aip poisoning. cardiovascular complications are poor prognostic factors in alp poisoning