The Max Planck Society is one of Europe’s most prestigious science funding agencies, but the new president, molecular biologist Peter Gruss, faces a tough challenge ahead with growing competition for research funds and the changing European and international landscape of research. Based in Germany, but with links in other European countries and beyond, the Max Planck Society (MPS) was establish...

Here we have characterized the putative Zn(II)2Cys6 transcription factor RosA from the filamentous fungus Aspergillus nidulans. The rosA gene encodes a protein of 713 aa, which shares 38% sequence similarity to Pro1 from Sordaria macrospora. In contrast to Pro1, which promotes the transition from protoperithecia to perithecia, RosA is a negative regulator of sexual development in A. nidulans. T...

ROSA is an e-learning system, which enables the creation, storage, reuse and management of Learning Objects (LOs). LO is a collection of reusable material used to support learning, education, or training. However, since ROSA is still a centralized system, it does not provide yet a complete integration of LOs created in local ROSAs of other institutions. This paper presents the evolution of ROSA...

The genus Rosa L. (Rosaceae) was recently treated floristically for North America, but range extensions and an additional taxon have been confirmed since then and are detailed here. These new reports document range extensions in the US and Canada of some native and introduced Rosa species, and new distributions and population data for several established Rosa hybrids (nothospecies). Some introd...

Transgenic overexpression of the Notch1 intracellular domain inhibits osteoblast differentiation and causes osteopenia, and inactivation of Notch1 and Notch2 increases bone volume transiently and induces osteoblastic differentiation. However, the biology of Notch is cell-context-dependent, and consequences of Notch activation in cells of the osteoblastic lineage at various stages of differentia...

Rosa: Tape 1, Side B The recording begins in a delicatessen. Rosa is with her mother and twin brother. Over the noise of cars passing the shop, Rosa’s mother can be heard ordering some Cabanas while Rosa sings a song by her favourite pop group 5ive. As they leave the shop, Rosa says goodbye to the shopkeeper who had given the twins a free meat pie each. Their mother asks them to wait until they...

In systemic mastocytosis (SM), clinical problems arise from factor-independent proliferation of mast cells (MCs) and the increased release of mediators by MCs, but no human cell line model for studying MC activation in the context of SM is available. We have created a stable stem cell factor (SCF) -dependent human MC line, ROSA(KIT WT), expressing a fully functional immunoglobulin E (IgE) recep...