Reduced sensitivity to thyroid hormone (TH) in peripheral tissues can occur as defects in TH transport into the cell, intracellular TH metabolism, cytosolic mechanisms, TH entry into the nucleus, thyroxin receptors (TRs) and receptor binding, transcription and post-transcriptional mechanisms. Current literature reveals an extensive list of mutations, drugs, toxins, metabolites and autoimmune an...

Seiring laju perkembangan kawasan terbangun di perkotaan berakibat pada peningkatan perubahan lahan. Salah satu dampak lahan menjadi area adalah berkurangnya Ruang Terbuka Hijau (RTH) yang berimplikasi terhadap meningkatnya suhu dan penurunan indeks kenyamanan kota. Tujuan dari penelitian ini menemukan areal memiliki potensi untuk dikembangkan sebagai (RTH). Parameter dalam menentukan prioritas...

resistance to thyroid hormone is an uncommon condition. we report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. rth is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary tsh secretion and refractoriness to hormone action in peripheral tiss...

Abstract: A procedure for determining the probability distribution of the rth order statistic, Gr:L, r 1⁄4 1, 2, . . . , L, among a set of L correlated Nakagami diversity branch gains G1, G2, . . ., GL has been described in David and Nagaraja (2003) and Elkashlan et al. (2008). The results are used to evaluate the bit error rate (BER) of general order selection (GOS), a diversity method in whic...

The syndrome of resistance to thyroid hormone (RTH) is characterized by elevated serum free thyroid hormones (FT4 and FT3) in the presence of unsuppressed TSH levels, reflecting resistance to the normal negative feedback mechanisms in the hypothalamus and pituitary. The degree of resistance within peripheral tissues determines whether thyrotoxic clinical features are associated with this condit...

Resistance to thyroid hormone (RTH) is a rare disorder characterized by variable tissue hyporesponsiveness to thyroid hormone, usually caused by mutations in the thyroid hormone receptor beta (TRbeta). We describe a large Brazilian family harboring a novel mutation affecting TRbeta gene and inducing RTH. A 14-year-old girl was found to have elevated free T4 and free T3 plasma concentrations in ...

Resistance to thyroid hormone (RTH) is a dominantly inherited condition of impaired tissue responsiveness to thyroid hormone (TH). Of variable severity, the presence of goiter, tachycardia, hyperactivity, or abnormal findings on routine laboratory tests usually lead to further investigation and, ultimately, the diagnosis of RTH. Characteristic thyroid function tests are elevated free thyroxine ...

For a graph G, its rth power is constructed by placing an edge between two vertices if they are within distance r of each other. In this note we study the amount of edges added to a graph by taking its rth power. In particular we obtain that, for r ≥ 3, either the rth power is complete or “many” new edges are added. In this direction, Hegarty showed that there is a constant ǫ > 0 such e(G3) ≥ (...

Physical development of public spaces was one the priority programs during Molen-Sopian administration as Mayor and Deputy Pangkalpinang for period 2018-2023. The availability space in urban areas refers to provisions distribution proportion Green Open Space (RTH), namely 20% Public (RTH) 10% Private (RTH). City Government is faced with dynamics politics which are colored by pros cons issues re...

Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...