UNLABELLED Using finite element analysis, we evaluated if the site of an aortic bleb, known to be prone to rupture, coincides with the location of peak wall stress (PWS) in a patient-specific abdominal aortic aneurysm (AAA) model. REPORT PWS was not located at the bleb site, even when stress values were estimated for different bleb wall thicknesses (0.5-2.0 mm) while the rest of the AAA wall ...

Over 1.9 million people suffer from eye injuries in the United States each year, occurring mainly from automobile accidents, sports related impacts, and military combat. A common injury prediction tool used for eye injuries is computational modeling, which requires accurate material properties to produce reliable results. The purpose of this study is to create a high rate pressurization system ...

The cardiovascular science community has pursued the quest to identify vulnerable atherosclerotic plaque in patients for decades, hoping to prevent acute coronary events. However, despite major advancements in imaging technology that allow visualization of rupture-prone plaques, clinical studies have not demonstrated improved risk prediction compared with traditional approaches. Considering the...

Creep deformation and rupture experiments are conducted on samples of the Ni-base superalloy directionally solidified GTD-111 tested at temperatures between 649°C and 982°C and two orientations (longitudinally and transversely oriented). The secondary creep constants are analytically determined from creep deformation experiments. The classical Kachanov–Rabotnov model for tertiary creep damage i...

CyberShake, as part of the Southern California Earthquake Center’s (SCEC) Community Modeling Environment, is developing a methodology that explicitly incorporates deterministic source and wave propagation effects within seismic hazard calculations through the use of physics-based 3D ground motion simulations. To calculate a waveform-based seismic hazard estimate for a site of interest, we begin...

BACKGROUND AND PURPOSE Cerebral artery aneurysms rupture when wall tension exceeds the strength of the wall tissue. At present, risk-assessment of unruptured aneurysms does not include evaluation of the lesions shape, yet clinical experience suggests that this is of importance. We aimed to develop a computational model for simulation of fluid-structure interaction in cerebral aneurysms based on...

BACKGROUND AND PURPOSE Rupture risk assessment for intracranial aneurysms remains challenging, and risk factors, including wall shear stress, are discussed controversially. The primary purpose of the presented challenge was to determine how consistently aneurysm rupture status and rupture site could be identified on the basis of computational fluid dynamics. MATERIALS AND METHODS Two geometri...

PURPOSE The purpose of this study is to give an overview of studies investigating the role of fludeoxyglucose F18 ((18)F-FDG) positron emission tomography (PET) scanning in patients with aortic aneurysms with a focus on molecular characteristics of the aneurysm wall. METHODS MEDLINE, EMBASE, and the Cochrane database were searched for relevant articles. After inclusion and exclusion, we selec...

BACKGROUND Adverse outcomes of pregnancy are a challenging health-care problem. Prediction of adverse pregnancy outcomes is important to prevent the morbidities of the foetus and the mother. AIMS To study the clinical interest of fetal nasal bone length in predicting adverse pregnancy outcomes in the first trimester of pregnancy. STUDY DESIGN A population-based retrospective cohort study. ...

OBJECTIVE In this study, we aimed to evaluate some laboratory and clinical factors in the prediction of latency period for pregnant patients complicated with preterm premature rupture of the membranes. MATERIALS AND METHODS Sixty-five pregnant patients between 24 and 34 weeks of gestation, who were admitted to University of Çukurova School of Medicine Hospital with the diagnosis of preterm pr...