BACKGROUND The effects of right ventricular apical pacing (RVAP) and right ventricular outflow tract (RVOT) septal pacing on atrial and ventricular electrophysiology have not been thoroughly compared. METHODS AND RESULTS To identify a more favorable pacing strategy with fewer adverse effects, 80 patients who had complete atrioventricular block with normal cardiac function and who were treated...

BACKGROUND The underlying mechanisms of Brugada syndrome (BrS) are not completely understood. Recent studies provided evidence that the electrophysiological substrate, leading to electrocardiogram abnormalities and/or ventricular arrhythmias, is located in the right ventricular outflow tract (RVOT). The purpose of this study was to examine abnormalities of epicardial and endocardial local unipo...

OBJECTIVES We sought to test whether the ratio of peak tricuspid regurgitant velocity (TRV, ms) to the right ventricular outflow tract time-velocity integral (TVI(RVOT), cm) obtained by Doppler echocardiography (TRV/TVI(RVOT)) provides a clinically reliable method to determine pulmonary vascular resistance (PVR). BACKGROUND Pulmonary vascular resistance is an important hemodynamic variable us...

Absent pulmonic valve (APV) in tetralogy of Fallot produces a pulmonic regurgitation murmur (PRM) which is usually late in onset after A2, low pitched, and of crescendo-decrescendo character. We have seen three adult patients with tetralogy of Fallot with APV and have done intracardiac sound and pressure studies in two. The PRM was loudest in the RV outflow tract (RVOT), where the onset was ear...

AIMS To determine pregnancy outcome and risk factors for adverse events in women with congenital heart disease (CHD) and residual haemodynamic right ventricular (RV) outflow tract (RVOT) lesions. METHODS AND RESULTS Pregnancy outcome data for women with CHD and residual RVOT lesions have been recorded since 2001. There were 76 pregnancies in 47 women that continued beyond 24 weeks gestation. ...

pathology affecting multiple sites of the right ventricle. However the predictive value of this finding is not 100% accurate. Early in the disease of ARVD/C one may see a single form of VT. There has also been a report of multiple forms of VT seen in an idiopathic VT, but the diagnosis in these rare instances must be carefully scrutinized. Niroomand et al. (2002) performed electrophysiology stu...

AIM To test a hypothesis attributing arrhythmia in Brugada Syndrome to right ventricular (RV) outflow tract (RVOT) conduction abnormalities arising from Nav 1.5 insufficiency and fibrotic change. METHODS Arrhythmic properties of Langendorff-perfused Scn5a+/- and wild-type mouse hearts were correlated with ventricular effective refractory periods (VERPs), multi-electrode array (MEA) measuremen...

BACKGROUND Recent studies suggest the significance of right ventricular (RV) function in the outcome in patients with left ventricular dysfunction (LVSD); however, global assessment of RV remains to be determined by echocardiogram because of its complex geometry. This study aimed to validate RV outflow tract fractional shortening (RVOT-FS) in the evaluation of RV function and its prognostic val...

Dear Sir, The report on “Right ventricular outflow tract (RVOT) systolic excursion (SE) and fractional shortening (FS)” is very interesting.[1] Allam et al. raised an interesting question, “Can these echocardiographic parameters be used for the assessment of right ventricular (RV) function?” Clinically, RV function assessment is useful for initial assessment, diagnosis, and follow-up of the pat...

Objective The aim of this study was to determine whether CARTO mapping is feasible in the right ventricle and assess its utility in guiding ablation of right ventricular outflow tract (RVOT) ventricualr tachycardia (VT). Background In patients with RVOT VT; CARTO mapping permits ablation guided by a VT complex, which may facilitate ablation of VT cases. However, the mapping system may be geomet...