Memory-related disorders are a common public health issue. Memory impairment is frequent in degenerative diseases (such as Alzheimer's disease and Parkinson disease), cerebral injuries, and schizophrenia. The dried stigma of the plant Crocus sativus L. (C. sativus), commonly known as saffron, is used in folk medicine for various purposes. Several lines of evidence suggest that C. sativus and it...

OBJECTIVE The aim of this double-blind and placebo-controlled trial was to investigate whether saffron (stigma of Crocus sativus L.) could relieve symptoms of premenstrual syndrome (PMS). DESIGN Double-blind, randomised and placebo-controlled trial. SETTING Departments of Gynaecology/Obstetrics and Psychiatry, Tehran and Zanjan University of Medical Sciences. POPULATION Women aged 20-45 y...

Saffron (Crocus sativus L.) is one of the world’s most valuable condiments, whose dried stigmas have been used since antiquity for culinary and medicinal purposes. The ethnobotanical data reveal that the plant and stigma extracts have many medicinal properties. On the basis of ethnobotanical data, lots of research has been done to determine the nutraceutical potential of saffron. The studies re...

Abstract Saffron ( Crocus sativus L., Iridaceae) is a highly valued species in the food, medicinal, and nutraceutical industries as coloring, flavoring, therapeutic agent. Its productivity flower production vary depending on different factors, including fertilizer treatment. This study was conducted to evaluate effects of inorganic (NK) combined with organic matter plant densities well influenc...

Crocus sativus is a triploid sterile plant with red stigmas belonging to family of Iridaceae, and sub Crocoideae. Crocin, picrocrocin, safranal are three major carotenoid derivatives that responsible for color, taste specific aroma Crocus. Saffron flowers harvested manually used as spice, dye or medicinal applications. The natural propagation rate most geophytes including saffron relatively low...

background: obesity is pandemic worldwide and a strong risk factor for cardio-metabolic disorders. the few approved anti-obesity drugs have poor efficacy and safety profile. thus, there is an urgent need for new anti-obesity agents. according to the traditional medicine and a clinical trial, saffron may have anorexigenic and anti-obesity effects which need further investigation. objectives: eva...

background: recent studies have indicated potential of saffron for applying in a wide variety of diseases such as psychiatric and neurologic disorders. the concurrent use of saffron with ssris can lead to reducing the dose of ssris. saffron at a dose of 200 mg may change some hematological and biochemical parameters. objective: the goal of this trial was to assess the safety of concomitant admi...

background: there is much debate about effects of medicinal plants such as saffron (crocus sativus) on human health. women are highly involved in farming and processing of this plant. this study is aimed at evaluating the saffron impacts on miscarriage rate of female farmers working in saffron fields. methods: this was a prospective case-control study on pregnant female farmers during harvestin...

islamic traditional medicine (itm) is a holistic system of medicine. saffron (crocus sativus) is one of the most famous plants cultivated in iran and has a wide range of activities such as oxytocic, anti-carcinogenic, exhilarant, anti-depressant, and anti-asthma effects. in addition, saffron can increase the bioavailability and enhance absorption of other drugs. this study comprises a bibliogra...

current therapies for breast cancer are often limited by short-term efficacy due to the emergence of drug resistance. there has been increased interest in the use of naturally occurring compounds with chemopreventive and chemotherapeutic effects in the treatment of cancers. saffron, dry stigmas crocus sativus l., used in iran as a spice, is known for its anticancer properties. in this study, th...