INTRODUCTION Typhoid fever is the most common illness caused by Salmonella typhi (S. typhi).(1) S. typhi bacteriuria can be seen following a recent episode of typhoid fever, or in chronic carrier state involving the urinary system, especially with local abnormalities of urinary tract.(2) However, S. typhi bacteriuria with renal stone disease has rarely been reported.(2) We presented a rare case...

Non-typhoidal Salmonella are infrequent causes of childhood meningitis. Most reports of Salmonella typhi meningeal infections are confined to neonates. A rare instance of S. typhi in an otherwise healthy eleven month old infant is being reported.

BACKGROUND Bloodstream infections (BSI) caused by Salmonella Typhi and invasive non-Typhoidal Salmonella (iNTS) frequently affect children living in rural sub-Saharan Africa but data about incidence and serotype distribution are rare. OBJECTIVE The present study assessed the population-based incidence of Salmonella BSI and severe malaria in a Health and Demographic Surveillance System in a ru...

Thirty-six Salmonella enterica serovar Typhi-specific genes, absent from the Salmonella enterica serovar Typhimurium genome, that were expressed in human macrophages were identified by selective capture of transcribed sequences. These genes are located on 15 unique loci of the serovar Typhi genome, including Salmonella pathogenicity islands (SPI-7, SPI-8, and SPI-10) and bacteriophages (ST15, S...

BACKGROUND Enteric fever is an important public health problem in many underdeveloped and developing countries. In India, though Salmonella enterica serotype Typhi remains the predominant Salmonella species causing enteric fever, isolation of Salmonella enterica serotype Paratyphi A is increasing. It occurs in all age groups and more common in summer season affecting mainly children. AIMS To ...

background and objectives:increased antibiotic resistance as a result of using antimicrobial drugs and also their various adverse effects has caused that in recent years, investigation of medicinal plants beconsidered for discovering new medicinal resources against bacterial infections. this study was performed with the objective of determining the antimicrobial activity of aqueous and ethanoli...

We experimentally identified and characterized 97 novel, non-protein-coding RNA candidates (npcRNAs) from the human pathogen Salmonella enterica serovar Typhi (hereafter referred to as S. typhi). Three were specific to S. typhi, 22 were restricted to Salmonella species and 33 were differentially expressed during S. typhi growth. We also identified Salmonella Pathogenicity Island-derived npcRNAs...

The propagation of Vi-phage I1 on ‘degraded Vi strains ’ of Salmonella typhi did not yield phage preparations bearing any trace of the specificity of the original Vi type from which the degraded strains had sprung. Ten different standard Vi-typing phages were grown on a selection of degraded Vi strains. The phages could be separated into two groups: six underwent a change which appeared to be a...

Salmonella typhi 5076-IC, which contains a plasmid that encodes the form I antigen of Shigella sonnei and which expresses S. typhi 9 and 12 and S. sonnei form I antigens, was used to immunize rabbits via chronically isolated ileal loops. Intestinal immunoglobulin A activity was detected against S. typhi, S. sonnei form I, and S. typhi strain 5076-IC. Thus S. typhi 5076-IC can effectively elicit...

Strains of the various Salmonella enterica serovars cause gastroenteritis or typhoid fever in humans, with virulence depending on the action of two type III secretion systems (Salmonella pathogenicity island 1 [SPI-1] and SPI-2). SptP is a Salmonella SPI-1 effector, involved in mediating recovery of the host cytoskeleton postinfection. SptP requires a chaperone, SicP, for stability and secretio...