SF3b is a U2 snRNP-associated protein complex essential for spliceosome assembly. Although evidence that SF3b contains the spliceosomal proteins SAPs 49, 130, 145, and 155 has accumulated, a protein-mediated association between all of these proteins has yet to be directly demonstrated. Here we report the isolation of a cDNA encoding SAP 130, which completes the cloning of the putative SF3b comp...

To explore the following hypotheses: 1) Gas exchange, Organ failure, Cause, Associated disease (GOCA) score, which reflects both general health and the severity of lung injury, would be a better mortality predictor of acute respiratory distress syndrome (ARDS) than acute physiology and chronic health evaluation (APACHE II) or simplified acute physiology score (SAPS II), which are not specific t...

BACKGROUND Several prognostic systems have been developed and validated in general Intensive Care Units (ICUs). No assessment of these scores was performed in specialized Gastroenterology Intensive Care Units (GICUs). AIM To assess the prognostic accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Simplified Acute Physiology Score (SAPS) II and Sequential Organ Failure Ass...

BACKGROUND End-of-life decision-making in Intensive care Units (ICUs) is difficult. The main problems encountered are the lack of a reliable prediction score for death and the fact that the opinion of patients is rarely taken into consideration. The Decision Curve Analysis (DCA) is a recent method developed to evaluate the prediction models and which takes into account the wishes of patients (o...

A statistical study has been performed by using two years of DMSP (Defense Meteorological Satellite Program) plasma observations to investigate the seasonal effect of SAPS (subauroral polarization stream) on the ion upflow in the duskside ionosphere of the Northern Hemisphere. There are obvious upflows occurring in the topside ionosphere around the SAPS region, exceeding 200 m s−1 at winter sol...

This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitt...

Xylella fastidiosa is a xylem-limited bacterium in plant hosts and causes Pierce's disease (PD) of grapevines, which differ in susceptibility according to the Vitis species (spp.). In this work we compared X. fastidiosa biofilm formation and population dynamics when cultured in xylem saps from PD-susceptible and -resistant Vitis spp. under different conditions. Behaviors in a closed-culture sys...

Mitochondria activation factor (MAF) is a high-molecular-weight polyphenol purified from black tea that activates mitochondrial respiration. It increased the mitochondrial membrane potential and motility of sea urchin sperm, by up to 8%, to the same extent as sperm-activating peptides (SAPs) secreted by the egg. Unlike SAPs, MAF had no effect on sperm swimming behavior, suggesting that the mech...

Using ground-based magnetic field measurements and numerical simulations from the Thermosphere-Ionosphere Electrodynamic General Circulation Model (TIEGCM), a first paper (Zhang, Yamazaki, et al., 2021, doi: https://doi.org/10.1029/2021JA029681; under review) introduced potential roles of disturbance dynamo electric due to subauroral polarization streams (SAPS) on equatorial electrojet (EEJ) du...

introduction: using physiologic scoring systems for identifying high-risk patients for mortality has been considered recently. this study was designed to evaluate the values of acute physiology and chronic health evaluation ii (apache ii) and simplified acute physiologic score (saps ii) models in prediction of 1-month mortality of critically ill patients. methods: the present prospective cross ...