PURPOSE Urolithiasis is a common urological disorder responsible for serious human affliction and cost to the society with a high recurrence rate. The aim of the present study was to systematically evaluate the phlorotannin rich extract of Sargassum wightii using suitable in vitro and in vivo models to provide scientific evidence for its antilithiatic activity. MATERIALS AND METHODS To explor...

Sargassum species are brown macroalgae found in shallow marine meadows. These are nutritious and rich source of several bioactive compounds. These isolated active compounds exhibit diverse biological activities like antioxidant, antiinflammatory, antipyretic, analgesic, antiviral, antidiabetic, hepatoprotective, anti-obesity, cholinesterase inhibitory activities etc. This makes the Sargassum sp...

OBJECTIVES This study aimed to elucidate the role and mode of action of Sargassum subrepandum methanolic extract in management of dyslipidemia in adult female rats. MATERIAL AND METHODS Forty adult female Sprague Dawley rats were assigned into four groups: (1) lean control rats fed on standard diet, (2) dyslipidemia control fed on the atherogenic diet, (3) lean rats orally administered with 1...

Feeding ecology of organisms associated with floating Sargassum in the northwestern Gulf of Mexico was assessed using fatty acids. Nineteen groups were collected from the Sargassum community including four autotrophs, eight invertebrates, five juvenile fishes, and two adult fishes. Spatial and temporal variability in polyunsaturated fatty acid (PUFA) signatures of selected taxa (Sargassum fluit...

Over the past 5 years, massive accumulations of holopelagic species of the brown macroalga Sargassum in coastal areas of the Caribbean have created "golden tides" that threaten local biodiversity and trigger economic losses associated with beach deterioration and impact on fisheries and tourism. In 2015, the first report identifying the cause of these extreme events implicated a rare form of th...

Two new compounds, asperversin A (1) and 9ξ-O-2(2,3-dimethylbut-3-enyl)brevianamide Q (2), and nine known compounds, brevianamide K (3), brevianamide M (4), aversin (5), 6,8-di-O-methylnidurufin (6), 6,8-di-O-methylaverufin (7), 6-O-methylaverufin (8), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (9), ergosta-7,22-diene-3β,5α,6β-triol (10), and 6β-methoxyergosta-7,22-diene-3β,5α-diol (11), were obtain...

Discovery of anticancer drugs that kill or disable tumor cells in the presence of normal cells without undue toxicity is a potential challenge for therapeutic care. Several papers in the literature have emphasized the potential implications of marine products such as seaweeds which exhibit antitumor activity. Study attempts to screen the antitumor effect of Sargassum sp, against chosen cell lin...

Budidaya ikan nila salin (Oreochromis sp.) memiliki permasalahan yaitu rendahnya tingkat pertumbuhan. Salah satu cara untuk mengatasi tersebut adalah dengan aplikasi pakan fungsional yang mengandung senyawa bioaktif meningkatkan Senyawa dapat diisolasi melakukan ekstrasi secara enzimatik menggunakan enzim protease. Penelitian ini bertujuan mengkaji pengaruh penambahan ekstrak Sargassum ilicifol...